Evidence map›Paper›PMID 40653450›Full record

ArticleJournal of biomedical materials research. Part A2025

Brillouin Spectroscopy: A Non-Invasive Method for Assessing the Viscoelastic Properties of Biologically Relevant Polymers.

Vsevolod Cheburkanov, Sujeong Jung, Mykyta Kizilov, Samantha E Holt, Daniel L Alge, Taylor H Ware, Vladislav V Yakovlev

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Label-Free Optical Investigation of Structural and Thermal Changes in Fat and Lean Beef under Frozen Storage.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vsevolod CheburkanovDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.
Sujeong JungDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.
Mykyta KizilovDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.
Samantha E HoltDepartment of Biological Engineering, Massachusetts Institute of Technology, Massachusetts, USA.
Daniel L AlgeDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.ORCID 0000-0002-8129-2871
Taylor H WareDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.
Vladislav V YakovlevDepartment of Biomedical Engineering, Texas A&M University, Texas, USA.ORCID 0000-0002-4557-1013

Funding

Brillouin Microscope for Biomedical ResearchR01GM127696 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2018 to 2021
$1.1M
Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopyR21CA269099 · NCI · TEXAS ENGINEERING EXPERIMENT STATION · PI BEREZIN, MIKHAIL Y., YAKOVLEV, VLADISLAV V. · 2022 to 2024
$577k
Sensing local nano-environment with coherent Raman microspectroscopyR21GM142107 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2021 to 2022
$399k
Air Force Office of Scientific ResearchNASANCI NIH HHS R21 CA269099NIGMS NIH HHS R01 GM127696NIGMS NIH HHS R21 GM142107NIH HHS
6 · The paper itself

Abstract

Research of biocompatible polymers is critical for advancing biomedical technologies, particularly in the fields of tissue engineering, drug delivery, and cardiovascular health. This study investigates the mechanical properties of a series of novel biocompatible polymers using Brillouin microspectroscopy. We demonstrate the ability of Brillouin spectroscopy to accurately measure mechanical properties of these polymers on a microscopic level, which are vital for their application and can be finely tuned to match the requirements. Our findings suggest that Brillouin microspectroscopy, coupled with Raman spectroscopy, offers a powerful complementary approach to traditional viscoelasticity measurement techniques, paving the way for enhanced characterization and utilization of biocompatible polymers in medical research and clinical practice. This in turn would help streamline production and control of these polymers in a non-invasive and label-free way.

Indexed as

Biocompatible MaterialsElasticityMaterials TestingPolymersSpectrum AnalysisSpectrum Analysis, RamanViscosityBiocompatible MaterialsPolymers

Identifiers

PMID40653450
PMCPMC12724586

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.