Evidence map›Paper›PMID 40653531›Full record

ArticleCardiovascular and interventional radiology2025

Prognostic Performance of Model for End-Stage Liver Disease (MELD) 3.0 for Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation.

Kenkichi Michimoto, Leonardo Campos, Spencer Cushen, Takeshi Suzuki, Kentaro Yamada, Willscott Naugler, Khashayar Farsad

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Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenkichi MichimotoDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA.
Leonardo CamposDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA.
Spencer CushenDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA.
Takeshi SuzukiDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA.
Kentaro YamadaDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA.
Willscott NauglerDivision of Gastroenterology and Hepatology, Oregon Health and Science University, 3485 S Bond Ave, Portland, OR, 97239, USA.
Khashayar FarsadDotter Department of Interventional Radiology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR, 97239-3011, USA. farsad@ohsu.edu.ORCID http://orcid.org/0000-0002-3127-7147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the prognostic performance of the model for end-stage liver disease (MELD) 3.0 in elective transjugular intrahepatic portosystemic shunt (TIPS) patients relative to MELD, MELD-Na, Freiburg index of post-TIPS survival, modified TIPS score, Child-Pugh, albumin-bilirubin, and chronic liver failure-consortium acute decompensation scores. MATERIALS AND

methodsA total of 342 patients (mean age: 55.5 years; 183 men) with portal hypertensive complications due to cirrhosis who underwent elective TIPS between December 2004 and June 2023 were reviewed. The prognostic performance of each scoring system for mortality at 30 days, 90 days, 1 year, and 3 years was evaluated using receiver operating characteristic curves to determine the area under the curve (AUC). Optimal cutoff values were determined accordingly. AUCs were compared using a bootstrap approach with 2000 resamples. Multivariable regression analyses were performed to identify independent risk factors.

resultsMELD 3.0 showed the highest AUC across the follow-up period. Compared to MELD and MELD-Na, MELD 3.0 showed significantly higher AUCs at 30 days (0.71, 0.71, and 0.82), 90 days (0.67, 0.68, and 0.77), 1 year (0.65, 0.69, and 0.77), and 3 years (0.63, 0.64, and 0.71) with corresponding P values of 0.049/0.022, 0.007/0.006, < 0.001/0.002, and 0.003/0.008, respectively. Regression analyses suggested MELD 3.0 as an independent risk factor for mortality, with a cutoff value of ≥ 19 for 30 day mortality (P < 0.001) and ≥ 17 for 90 day, 1 year, and 3 year mortality (P < 0.001).

conclusionMELD 3.0 may serve as a reliable prognostic tool compared to other existing scoring systems, acutely and in the longer term for elective TIPS creation. LEVEL OF EVIDENCE: Level 3, Retrospective single-center cohort study.

Indexed as

End Stage Liver DiseaseHypertension, PortalLiver CirrhosisPortasystemic Shunt, Transjugular IntrahepaticAdultAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesSeverity of Illness IndexLiver transplantationMELDTransjugular intrahepatic portosystemic Shunt; TIPS

Identifiers

PMID40653531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.