ArticleEnvironmental science & technology2025
Isotopic Fractionation of Natural Uranium in Mice as a Potential Biomarker of Renal Accumulation.
Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Uranium Isotopes: From Geosciences to Biomedical Sciences.Current environmental health reports · 2026Review
- Associations of drinking water and urinary uranium with incident diabetes among U.S. adults: The Multi-Ethnic Study of Atherosclerosis and the Strong Heart Family Study.Environmental research · 2026Article
- Isoscapes as a Regional-Scale Tool for Tracing Groundwater Uranium Cycling in the Northern Plains, United States.Environmental science & technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Chronic low-level uranium (U) exposure through drinking water is a public health risk in the United States. Nearly two-thirds of community water systems, serving 320 million people, have detectable U levels, with 2% exceeding the EPA's maximum contaminant level of 30 μg/L. Ingested U accumulates in kidneys and is nephrotoxic at high levels. Uranium binds to proximal tubule cells, causing injury and interfering with kidney function. Epidemiological studies suggest that even low-level (<30 μg/L) of U exposure could damage kidneys. Current biomarkers, like urinary U levels, fail to indicate tissue-specific concentrations and metabolic interactions in kidneys. Fractionation of
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.