ArticleJournal of dental sciences2025
Exploring gender-specific prognostic factors and survival outcomes in oral squamous cell carcinoma: Insights from a Taiwanese cohort.
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Impact of the surgery to radiotherapy interval on oncological outcomes in squamous cell carcinoma of the oral tongue.Discover oncology · 2026Article
- The efficacy and safety of tislelizumab combined with weekly nab-paclitaxel, carboplatin, and cetuximab as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a real-world study.Frontiers in immunology · 2025Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: /purpose: Oral squamous cell carcinoma (OSCC) is a prevalent malignancy in Taiwan, with sex-specific variations in risk factors, clinical presentation, and prognosis. This study aimed to evaluate the clinicopathological characteristics and survival outcomes of a larger cohort of male and female OSCC patients treated at National Taiwan University Hospital (NTUH) between 2012 and 2022. Materials and methods: A retrospective review of 240 de-identified, sex- and age-matched OSCC patients was conducted, analyzing clinicopathological characteristics, lifestyle habits (alcohol, betel quid, smoking), and survival outcomes. Results: Gender differences were observed in tumor location, with males more likely to have buccal mucosa cancer and females more frequently diagnosed with tongue cancer. Survival analysis showed no significant sex differences in overall survival (OS), but oral habits, oral ulcer, xerostomia and menopause significantly influenced female prognosis. Multivariate analysis identified age, tumor location, and oral habits as independent factors affecting survival. Conclusion: Sex-specific factors, including age, lifestyle, and oral health conditions, contribute to OSCC prognosis. Tailored therapeutic strategies are necessary to address these gender-based disparities and improve survival outcomes for all OSCC patients.
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Registered trials
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