Evidence map›Paper›PMID 40654493›Full record

ArticleJournal of dental sciences2025

Is periodontitis a potential risk factor of rhegmatogenous retinal detachment? A population-based retrospective cohort study of Taiwan.

Earl Fu, Yueh-Ju Tsai, Chi-Hsiang Chung, Min-Wen Fu, Yi-Jan Hsia, Wu-Chien Chien

Abstract read
In one paragraph

Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Earl FuDepartment of Dentistry, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Xindian, New Taipei City, Taiwan.
Yueh-Ju TsaiDepartment of Ophthalmology, Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.
Chi-Hsiang ChungDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Min-Wen FuDepartment of Endodontics, New York University College of Dentistry, New York, USA.
Yi-Jan HsiaDepartment of Dentistry, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Xindian, New Taipei City, Taiwan.
Wu-Chien ChienDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Purpose: Periodontitis, a common inflammatory disease, has been linked to various systemic and ocular conditions. However, its connection to rhegmatogenous retinal detachment (RRD), a vision-threatening condition, remains uncertain. This study aimed to investigate the association between periodontitis and RRD. Materials and methods: From 2000 to 2015, 1,936,512 participants were recruited from Taiwan's National Health Insurance Research Database, including 29,970 with chronic periodontitis, defined by at least three outpatient visits within a year. A matched 1:1 comparison group was selected based on sex, age, and index year. The periodontitis group was divided into two subgroups: those who received root planing and/or surgical therapy (subgroup 1) and those who did not (subgroup 2). Results: At the end of the follow-up, 2165 participants in the periodontitis group and 1259 in the comparison group developed RRD. The cumulative risk of RRD was increased in the periodontitis group, and the two subgroups, compared to the comparison group. After adjustment with the covariates of sociodemographic factors, systemic diseases, RRD comorbidities, and smoking/alcohol habits, the increased risk of developing RRD remained significant (adjusted hazard ratio: 1.49, 95 % CI: 1.12-1.83, Conclusion: This nationwide retrospective study showed that patients with chronic periodontitis, regardless of whether they received periodontal treatment, had a higher risk of developing RRD, suggesting a potential association between periodontitis and RRD.

Indexed as

DatabaseNational health programsPeriodontitisRetinal detachmentTaiwanese

Identifiers

PMID40654493
PMCPMC12254779

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.