Evidence map›Paper›PMID 40654534›Full record

ArticleFood science & nutrition2025

Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.

Zhongliang Liu, Jiena Ye, Jiachen Xi, Qingping Li, Yunping Tang, Yizhou Tian, Dongxu Wang, Zuisu Yang, Yaping Ding

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Longchai Decoction Treated the Fibrosis of Liver Induced by CClJournal of cellular and molecular medicine · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhongliang LiuZhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University Zhoushan China.
Jiena YeSchool of Food and Pharmacy Zhejiang Ocean University Zhoushan China.
Jiachen XiZhejiang Chinese Medical University Hangzhou China.
Qingping LiZhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University Zhoushan China.
Yunping TangSchool of Food and Pharmacy Zhejiang Ocean University Zhoushan China.
Yizhou TianZhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University Zhoushan China.
Dongxu WangSchool of Grain Science and Technology Jiangsu University of Science and Technology Zhenjiang China.ORCID https://orcid.org/0000-0001-7377-6190
Zuisu YangSchool of Food and Pharmacy Zhejiang Ocean University Zhoushan China.
Yaping DingZhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University Zhoushan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis, closely linked to oxidative stress, remains a significant global health challenge. Fucoxanthin (Fx), a marine carotenoid extracted from brown algae, exhibits potent antioxidant properties, yet its molecular mechanism in liver fibrosis remains unclear. In the present study, a murine model of liver fibrosis was established through intraperitoneal injection of carbon tetrachloride (CCl

Indexed as

ferroptosisfucoxanthinglutathione peroxidase 4liver fibrosisNrf2

Identifiers

PMID40654534
PMCPMC12245720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.