Evidence map›Paper›PMID 40655137›Full record

ReviewFrontiers in immunology2025

Exploring the genetic basis of Newcastle disease virus in chickens: a comprehensive review.

Haile Berihulay, Wei Luo, Ainong Lao, Jian Ji, Manshan Cai, Dingming Shu, Chenglong Luo

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haile Berihulay *State Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Wei Luo *State Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Ainong LaoState Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Jian JiState Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Manshan CaiState Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Dingming ShuState Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Chenglong LuoState Key Laboratory of Swine and Poultry Breeding Industry Guangdong Key Laboratory of Animal Breeding and Nutrition Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND) is one of the most serious viral diseases affecting chickens and is caused by Newcastle disease virus (NDV), an avian paramyxovirus serotype-1. The virus contains five structural proteins and two nonstructural proteins that interact with the host proteins involved in viral infection and host antiviral responses. Currently, several NDV strains have been molecularly characterized; however, a comprehensive overview of NDV in chickens that addresses recent findings is lacking. This review summarizes the current report of the molecular structure of NDV, including candidate genes and genomic regions, virulence and route of infection, mechanisms of resistance, host immune response, disease resistance mechanisms and effects of NDV on chicken immune performance. Therefore, this review can be used by researchers seeking a comprehensive understanding that can be applied in future breeding programs aimed at enhancing disease resistance.

Indexed as

ChickensNewcastle DiseaseNewcastle disease virusPoultry DiseasesAnimalsDisease ResistanceHost-Pathogen InteractionsVirulencechickengenetic resistanceimmune responsemolecular structureNDVpathogenesis

Identifiers

PMID40655137
PMCPMC12245680

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.