Evidence map›Paper›PMID 40655429›Full record

ArticleCoordination chemistry reviews2025

Application of smart responsive nanomaterials in the theranostics of gastrointestinal malignancies: Current status and future perspectives.

Wenpeng Huang, Jingwei Zhou, Yutong Liang, Rachel J Saladin, Liming Li, Lei Kang, Chen Hua, Weibo Cai

Abstract read
In one paragraph

Article in Coordination chemistry reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Applications of Nanobiotechnology in Medicine.Life (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenpeng HuangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Jingwei ZhouDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Yutong LiangMichigan State University College of Osteopathic Medicine, East Lansing, MI 48824, USA.
Rachel J SaladinDepartments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI 53705, USA.
Liming LiDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China.
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Chen HuaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI 53705, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

Gastrointestinal (GI) malignancies remain to be one of the most prevalent malignancies that are often characterized by a dismal prognosis. Nanoplatforms present a groundbreaking avenue for enhancing targeting strategies and multifunctionality in cancer treatment. The emergence of nanotechnology, particularly the innovation of smart responsive nanomaterials, has revolutionized cancer diagnosis and therapy. This review begins by exploring the design principles of smart responsive nanomaterials, focusing on the various exogenous and endogenous stimuli that drive their functionality. Furthermore, we provide a comprehensive summary of the applications of smart responsive nanomaterials in the treatment of GI malignancies over the past five years. Our aim is to contribute to the growing body of knowledge on smart responsive nanomaterials in GI malignancies, spark innovative ideas, and encourage further advancements in this field. Finally, we discuss the prospects and challenges associated with the use of smart responsive nanomaterials in GI malignancies.

Indexed as

Drug deliveryGastrointestinal malignanciesIntelligent responsesNanomedicineSmart responsive nanomaterialsTheranostics

Identifiers

PMID40655429
PMCPMC12245206

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.