Evidence map›Paper›PMID 40656459›Full record

ArticleNew journal of physics2025

Enhanced extracellular matrix remodeling due to embedded spheroid fluidization.

Tao Zhang, Shabeeb Ameen, Sounok Ghosh, Kyungeun Kim, Mrinal Pandey, Brian C H Cheung, Minh Thanh, Alison E Patteson, Mingming Wu, J M Schwarz

Abstract read
In one paragraph

Article in New journal of physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. A microfluidic rheometer for tumor mechanics and invasion studies.bioRxiv : the preprint server for biology · 2025
    Article
  8. Vimentin - Force regulator in confined environments.Current opinion in cell biology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tao ZhangSchool of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.ORCID https://orcid.org/0000-0002-7636-0913
Shabeeb AmeenDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.
Sounok GhoshDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.
Kyungeun KimDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.ORCID https://orcid.org/0000-0001-5211-434X
Mrinal PandeyDepartment of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, United States of America.ORCID https://orcid.org/0000-0001-8941-4290
Brian C H CheungDepartment of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, United States of America.
Minh ThanhDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.
Alison E PattesonDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.ORCID https://orcid.org/0000-0002-4004-1734
Mingming WuDepartment of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, United States of America.ORCID https://orcid.org/0000-0001-7846-3580
J M SchwarzDepartment of Physics and BioInspired Institute, Syracuse, Syracuse University, Syracuse, NY 13244, United States of America.

Funding

Microfluidic platform for tumor cell invasionR01CA221346 · NCI · CORNELL UNIVERSITY · PI Mingming Wu · 2017 to 2026
$3.4M
Role of vimentin in mammalian cell motilityR35GM142963 · NIGMS · SYRACUSE UNIVERSITY · PI PATTESON, ALISON ELISE · 2021 to 2025
$2.1M
UltraVIEW VoX spinning disk confocal for core facilityS10OD010605 · OD · CORNELL UNIVERSITY · PI WILLIAMS, REBECCA M · 2012 to 2012
$595k
NCI NIH HHS R01 CA221346NIGMS NIH HHS R35 GM142963NIH HHS S10 OD010605
6 · The paper itself

Abstract

Embedding a collective of tumor cells, i.e. a tumor spheroid, in a fibrous environment, such as a collagen network, provides an essential

Indexed as

biophysical computational modelingcell–extracellular matrix interactionsembedded spheroidmulticellular interactions

Identifiers

PMID40656459
PMCPMC12242829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.