Evidence map›Paper›PMID 40656613›Full record

ReviewWorld journal of gastroenterology2025

Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets.

Nevena M Gajovic, Ivan P Jovanovic, Miodrag V Jocic, Bojan Stojanovic, Irfan F Corovic, Nevena Todorovic, Bojana J Simovic Markovic, Amedeo Amedei

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nevena M GajovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, Serbia.
Ivan P JovanovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, Serbia.
Miodrag V JocicInstitute for Transfusiology and Haemobiology, Military Medical Academy, Belgrade 11000, Serbia.
Bojan StojanovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, Serbia.
Irfan F CorovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, Serbia.
Nevena TodorovicDepartment of Experimental and Clinical Medicine, University of Florence, Florence 50134, Italy.
Bojana J Simovic MarkovicCenter for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, Serbia. bojana.simovic@gmail.com.
Amedeo AmedeiDepartment of Experimental and Clinical Medicine, University of Florence, Florence 50134, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cancer remains one of the leading causes of cancer-related mortality worldwide, with hepatocellular carcinoma representing its most prevalent form. This review provides a comprehensive summary of the key factors driving the initiation and progression of hepatocellular carcinoma, with a particular emphasis on immune-related mechanisms. Furthermore, we delve into the emerging roles of galectins, particularly galectin-1 and galectin-3, in hepatocellular carcinoma pathobiology, underscoring their potential utility as biomarkers for assessing disease severity and progression. These insights contribute to a better understanding of the molecular and immunological underpinnings of hepatocellular carcinoma, paving the way for more targeted therapeutic strategies.

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularGalectinsLiver NeoplasmsDisease ProgressionGalectin 1Galectin 3HumansLiverMolecular Targeted TherapyTumor MicroenvironmentBiomarkers, TumorGalectin 1Galectin 3GalectinsBiomarkersGalectin-1Galectin-3GalectinsHepatocellular carcinomaImmunopathogenesisLiver cancer

Identifiers

PMID40656613
PMCPMC12243866

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.