Evidence map›Paper›PMID 40656782›Full record

ArticleCardiovascular diagnosis and therapy2025

Comparison of clinical features and outcomes of Chinese patients with Takotsubo syndrome and acute myocardial infarction-results from the first Chinese Takotsubo syndrome registry.

Yuxi Huang, Lingchun Lyu, Yuan Tao, Juan Lei, Yulin Wei, Liwen Wu, Mei Xu, Yusheng Liu, Lingzhi Jiang, Zhongxia Sun and 10 more

Abstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yuxi Huang *Department of Cardiovascular Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Lingchun Lyu *Department of Cardiology, Lishui Hospital of Zhejiang University School of Medicine, Lishui, China.
Yuan Tao *Department of Cardiology, Sheng Zhou People's Hospital, Shengzhou, China.
Juan LeiDepartment of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Yulin WeiDepartment of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Liwen WuDepartment of Ultrasound, The Sixth Affiliated Hospital of Guangzhou Medical University/Qingyuan People's Hospital, Qingyuan, China.
Mei XuDepartment of Cardiovascular Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Yusheng LiuDepartment of Cardiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lingzhi JiangCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Zhongxia SunDepartment of Ultrasound Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yongmin DingDepartment of Respiratory and Critical Care Medicine, Shengzhou People's Hospital, Shengzhou, China.
Pengfei MiaoDepartment of Cardiology, Linfen Central Hospital, Linfen, China.
Qianglin GuanDepartment of Cardiovascular Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Feng LvDepartment of Cardiology, Sheng Zhou People's Hospital, Shengzhou, China.
Cunxue PanDepartment of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Chenying LuDepartment of Radiology, Lishui Hospital of Zhejiang University School of Medicine, Lishui, China.
Yuyi ChenDivision of Cardiology, Heart and Vascular Center, Washington University in St Louis, Barnes-Jewish Hospital, St. Louis, MO, USA.
Tou Kun Chong *Department of Cardiology, Kiang Wu Hospital, Macao, China.
Kan Liu *Division of Cardiology, Heart and Vascular Center, Washington University in St Louis, Barnes-Jewish Hospital, St. Louis, MO, USA.
Jian Chen *Department of Cardiovascular Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Takotsubo syndrome (TTS) differs significantly from acute myocardial infarction (AMI) in clinical features and pathological mechanisms, but evidence in Asian populations remains limited. The aim of this study is to compare clinical features and outcomes between patients with TTS and AMI in the first Chinese registry of TTS (ChiTTS Registry, ChiCTR1900026725). Methods: In this multicenter 6-year retrospective cohort study (February 2016-June 2022), a total of 116 consecutive TTS patients diagnosed according to the international Takotsubo diagnostic criteria and 232 age- and sex-matched AMI patients (1:2 ratio) meeting the 2023 European Society of Cardiology guidelines criteria were enrolled from 10 tertiary medical centers across China. Clinical characteristics, in-hospital outcomes, and major adverse cardiovascular and cerebrovascular events (MACCEs) were compared between groups using Student's Results: The median follow-up time was 1.23 [interquartile range (IQR), 0.33-2.63] years in ChiTTS Registry patients and 2.35 (IQR, 1.68-3.68) years in AMI patients. In contrast to AMI patients, TTS patients presented with more clinical manifestations associated with acute heart failure. TTS patients developed approximately twice as many in-hospital complications as AMI patients (42.2% Conclusions: In comparison to AMI patients, Chinese TTS patients developed more in-hospital complications and had a worse short-term prognosis. The cardiovascular issues in TTS patients underscore the need for effective treatment and personalized strategies to enhance outcomes and mitigate risks.

Indexed as

acute myocardial infarction (AMI)characteristicsChineseprognosisTakotsubo syndrome (TTS)

Identifiers

PMID40656782
PMCPMC12246995

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.