ArticleDrug design, development and therapy2025
A Bibliometric Study of Interleukin Cytokines in the Treatment of Intervertebral Disc Degeneration.
Article in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bridging the innovation-evidence chasm: a critical appraisal and roadmap for robotic pancreatic cancer surgery.Journal of robotic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In recent years, the research on the occurrence and development of interleukin in intervertebral disc degeneration has been more and more extensive. The purpose of this study is to predict the future research direction or prospect by analyzing the relevant literature in this field. Objective: Interleukin family cytokines are becoming more and more important in the research field of intervertebral disc degeneration, but all previous studies only focus on one aspect and are not comprehensive. We revealed the most influential countries and institutions in the field of interleukin, cytokine and intervertebral disc therapy. Systematic analysis of interleukin family cytokines and intervertebral disc degeneration and summary of related mechanisms will help to further promote the progress of related clinical treatment. Methods: The related articles published in 1 January 2015-1 December 2024 were all from network science (WOS), and charts were made and analyzed by using social science statistics software package and GraphPad Prism 8 software. Using VOS viewer software and CiteSpace software, the research trend of keywords is analyzed visually. Results: China has made the most significant contribution in this field. In addition, the research papers on IL-1 cytokines and intervertebral disc degeneration are the most, and Huazhong University of Science and Technology has published the most papers. Spine is the magazine that publishes the largest number of related documents. Preclinical medicine, especially immunology, plays a key role in this field. In hot spots, the focus of research can be divided into two parts (intervertebral disc degeneration and nucleus pulposus cells; The expression of interleukin and cytokine). Conclusion: This marks the first bibliometric analysis in this field and provides a comprehensive literature overview. Our findings clarify the future research direction and various cooperative relationships. Targeted therapy for interleukin and cytokine may be an important development trend in the future.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.