Evidence map›Paper›PMID 40657820›Full record

ArticleFuture medicinal chemistry2025

Design, synthesis,

Vivek Panwar, Yajat Rohila, Aishwarya Singh, Meenakshi, Bhavana Singh, Manoj K Gupta, Manoj Garg, Deepak Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vivek PanwarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, India.
Yajat RohilaDepartment of Chemistry, Central University of Haryana, Mahendergarh, India.
Aishwarya SinghAmity Institute of Molecular Medicine and Stem Cell Research, Amity University Uttar Pradesh, Noida, India.
MeenakshiDepartment of Chemistry, Central University of Haryana, Mahendergarh, India.
Bhavana SinghAmity Institute of Molecular Medicine and Stem Cell Research, Amity University Uttar Pradesh, Noida, India.
Manoj K GuptaDepartment of Chemistry, Central University of Haryana, Mahendergarh, India.
Manoj GargAmity Institute of Molecular Medicine and Stem Cell Research, Amity University Uttar Pradesh, Noida, India.
Deepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, India.ORCID 0000-0003-2241-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMATERIALS AND

methodsA series of RESULTS AND

conclusion5 l and 5 h suppressed the growth of MIA PaCa-2 cancer cells and were very less cytotoxic to hTERT-HPNE cells. Additionally, the anticancer efficacy was confirmed against PANC-1 and MCF-7 for

Indexed as

Antineoplastic AgentsDrug DesignHydrazonesSTAT3 Transcription FactorApoptosisCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsHydrazonesSTAT3 protein, humanSTAT3 Transcription Factorapoptosiscell-cyclecytotoxicitymolecular docking and dynamicN-acylhydrazonespancreatic and breast cancerSTAT3 and JAK1synthesis

Identifiers

PMID40657820
PMCPMC12309538

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.