Evidence mapPaperPMID 40658159Full record

ReviewThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2025

Epicardial adipose tissue in type 1 diabetes mellitus: a systematic review and meta-analysis.

Basavaraj G Sooragonda, Vanshika Karnwal, Vikneswaran Gunaseelan, Ameya Joshi, Kaushik Biswas, Mohan T Shenoy, Rakesh Anbazhagan

Abstract readReview
In one paragraph

Review in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Basavaraj G SooragondaNarayana Health Bengaluru, Bengaluru, India.
Vanshika KarnwalNarayana Hrudayalaya Institute of Allied Health Sciences, Bengaluru, India.
Vikneswaran GunaseelanNarayana Health Bengaluru, Bengaluru, India.
Ameya JoshiBhaktivedanta Hospital And Research Institute, Mira-Bhayandar, India.
Kaushik BiswasMedica Superspecialty Hospital, Kolkata, India.
Mohan T ShenoySree Gokulam Medical College and Research Foundation, Thiruvananthapuram, India.
Rakesh AnbazhagancoGuide Academy, Bengaluru, India. anbazhaganrakesh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpicardial adipose tissue (EAT) is a metabolically active visceral fat depot surrounding the myocardium and evidence suggests its potential role in the development of cardiovascular complications in type 1 diabetes mellitus (T1DM). This systematic review and meta-analysis aimed to: (1) quantify EAT measurements (thickness and volume) in patients with T1DM, and (2) compare EAT measurements between T1DM patients and healthy controls.

methodsA comprehensive literature review was conducted using a systematic search strategy to identify studies that measured EAT thickness or volume in T1DM patients in PubMed, Embase, Cochrane Library, Web of Science, and CINAHL. Studies were included if they: (1) involved patients with T1DM, (2) reported EAT measurements using imaging techniques, and (3) were published in English. Case reports and reviews were excluded. Two independent reviewers performed study selection, data extraction, and quality assessment. Study quality was evaluated using the Newcastle-Ottawa Scale (NOS). Statistical heterogeneity was assessed using I

resultsA total of nine studies involving 285 and 233 participants measuring thickness and volume with T1DM were included. The pooled mean EAT thickness was 5.81 mm (95%CI: 4.30, 7.32 mm), and the pooled mean EAT volume was 56.84cm

conclusionsOur findings indicate increased EAT measurements in T1DM patients compared to healthy individuals, suggesting EAT's potential involvement in T1DM-related cardiovascular issues.

Indexed as

Cardiovascular diseasesEpicardial adipose tissueMeta-analysisSystematic reviewType 1 diabetes mellitus

Identifiers

PMID40658159
PMCPMC12259519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.