Evidence map›Paper›PMID 40658446›Full record

ReviewVirulence2025

A comprehension and systematic insight into the interaction between ferroptosis and virus infection: The implications of mechanisms and strategies.

Sai Niu, Yian Deng, Yonggen Yang, Junjie Wang, Chunyue Fang, Ying Zhou, Hanchuan Dai

Abstract readReview
In one paragraph

Review in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sai NiuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Yian DengCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Yonggen YangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Junjie WangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Chunyue FangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Ying ZhouCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Hanchuan DaiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.ORCID 0000-0001-6753-9703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a novel form of iron-dependent programmed cell death characterized by iron metabolic derangement, an abnormal antioxidant system, and lipid peroxidation. Emerging evidence revealed that viruses modulate ferroptosis to facilitate their replication, dissemination, and pathogenesis, thereby promoting infection or achieving immune evasion by hijacking the host's iron metabolism. However, the interplay between ferroptosis and virus infections remains to be elucidated. This review comprehensively summarizes the core mechanisms of ferroptosis, including iron homeostasis, the system Xc

Indexed as

FerroptosisHost-Pathogen InteractionsVirus DiseasesAnimalsHomeostasisHumansIronLipid PeroxidationVirusesIronCell deathFerroptosisiron metabolismlipid peroxidationvirus infection

Identifiers

PMID40658446
PMCPMC12269692

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.