Evidence map›Paper›PMID 40658776›Full record

ArticleChemistry & biodiversity2025

Extraction of Triterpene Compounds From Hancornia speciosa Gomes Fruits and Evaluation of Pharmacological Potential.

Sérgio Prado Leite, Michel Rubens Dos Reis Souza, Adilson Allef Moraes Santana, Monalisa Martins Montalvão, Camilla Natália Oliveira Santos, Lucas Sousa Magalhães, Cristiane Bani Correa, Tatiana Rodrigues de Moura, Sona Jain, Thiago Rodrigues Bjerk

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sérgio Prado LeiteUniversidade Tiradentes, Aracaju, Brazil.
Michel Rubens Dos Reis SouzaUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Adilson Allef Moraes SantanaUniversidade Tiradentes, Aracaju, Brazil.
Monalisa Martins MontalvãoUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Camilla Natália Oliveira SantosUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Lucas Sousa MagalhãesUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Cristiane Bani CorreaUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Tatiana Rodrigues de MouraUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Sona JainUniversidade Federal de Sergipe, Sao Cristovao, Brazil.
Thiago Rodrigues BjerkUniversidade Tiradentes, Aracaju, Brazil.ORCID https://orcid.org/0000-0003-0067-6804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hancornia speciosa Gomes, a Brazilian native species, holds biotechnological potential due to compounds such as lupeol, α-amyrin, and β-amyrin, which possess pharmacological properties. This study investigates triterpene-rich extracts from H. speciosa fruit for potential anti-inflammatory applications. Extraction was performed using the energized-guided dispersive extraction (EDGE) method and compared to ultrasound extraction techniques to evaluate efficiency and yield. The EDGE system demonstrated notable advantages over ultrasound extraction, including a 60 mL reduction in solvent volume and an 87-min decrease in extraction time, enhancing efficiency, cost-effectiveness, and sustainability. The EDGE extraction successfully obtained a triterpene-rich extract from H. speciosa Gomes with a concentration of lupeol (50.09 ± 1.29 mg/g) with no significant difference when compared to the extract obtained by ultrasound (49.95 ± 2.54 mg/g). The extract showed no cytotoxicity and irritation in the hen's egg test-chorioallantoic membrane assay and significantly reduced reactive oxygen species produced by neutrophils. These results indicate the extract's phytotherapeutic potential, suggesting new possibilities for future studies and therapeutic applications, and highlight EDGE as a promising technique for phytotherapeutic applications.

Indexed as

Anti-Inflammatory AgentsApocynaceaeFruitPlant ExtractsTriterpenesAnimalsCell SurvivalNeutrophilsReactive Oxygen SpeciesAnti-Inflammatory AgentsPlant ExtractsReactive Oxygen SpeciesTriterpeneschromatographyHancornia speciosamangabamedicinal plants

Identifiers

PMID40658776
PMCPMC12629162

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.