ArticleBMC pregnancy and childbirth2025
Metformin use in gestational diabetes is not associated with an increased risk of preterm labor and small for gestational age infants compared to diet control alone.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Gestational Diabetes Diagnosed Early in Pregnancy: Effects on Pregnancy Outcomes and Gestational Weight Gain.International journal of endocrinology · 2026Article
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsGiven the limited data on the effects of metformin exposure in pregnancy, this study aims to investigate the association between metformin use in Gestational Diabetes (GDM) and the risk of short-term maternal and neonatal outcomes.
methodsThis retrospective cohort study included women with GDM who sought prenatal care at Sidra Medicine, Qatar, between January 2019 and December 2020 and compared maternal and neonatal outcomes in patients treated with metformin to those treated with diet control alone.
resultsSix hundred forty nine GDM patients were included, of which 438 were treated with diet only, and 211 were treated with metformin. At baseline, the metformin-treated group was older (33.3 ± 4.8 vs. 31.2 ± 5.0 years), had higher pre-pregnancy Body Mass Index (BMI) (27.9 ± 4.6 vs. 26.0 ± 4.7 kg/m
conclusionsTreatment with metformin was not associated with an increased risk of adverse outcomes, including small for gestational age and preterm labor in women with GDM.
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Registered trials
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