Evidence map›Paper›PMID 40661245›Full record

ArticleFrontiers in neurology2025

Study on the relationship between sleep-wake states and prognosis in patients with intracranial arterial stenosis and ischemic stroke.

Xiaodong Yuan, Jing Xue, Yongshan Fu, Ya Ou, Ying Zhao, Cuiping Yan, Pingshu Zhang

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaodong Yuan *Department of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Jing Xue *Department of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Yongshan FuDepartment of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Ya OuDepartment of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Ying ZhaoDepartment of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Cuiping YanDepartment of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.
Pingshu ZhangDepartment of Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the influence of the sleep-wake state on the prognosis of patients with ischemic stroke. Methods: Consecutive patients with intracranial ischemic stroke due to arterial stenosis were included (198 cases). The control group consisted of contemporaneous patients without cerebrovascular stenosis or any diagnosed cerebrovascular disease (77 cases). Collect the following variables of the patients, including the total recording time during the day and night, total sleep time, sleep latency, rapid eye movement (REM) sleep latency, wake time after falling asleep, light sleep stage (N1, N2 stage), deep sleep stage (N3 stage), and non-rapid eye movement (non-rapid eye movement) (NREM) sleep stage, rapid eye movement (REM) sleep stage, and stroke topography (anterior circulation and posterior circulation ischemic stroke). The primary outcome was the functional status at discharge, evaluated using the modified Rankin Scale (mRS): good prognosis (mRS ≤ 2) and poor prognosis (mRS > 2). Results: In the regression analysis of prognostic influencing factors in patients with ACIS, it was concluded that an increase in daytime deep sleep time was associated with an increased possibility of adverse outcomes in patients with ACIS ( Conclusion: The sleep-wake state of patients with intracranial artery stenoischemic stroke changes. The main characteristics are increased diurnal sleep, increased incidence of daytime sleep, and disordered sleep-wake phases. In patients with ACIS, the diurnal sleep-wake biological rhythm mainly characterized by poor daytime stability is unbalanced. The longer the duration of daytime deep sleep and nighttime NREM sleep, the higher the possibility of adverse outcomes in patients with intracranial artery stenotic ischemic stroke.

Indexed as

intracranial arterial stenosisischemic strokeprognosisprognostic factors analysissleep–wake state

Identifiers

PMID40661245
PMCPMC12256223

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.