Evidence map›Paper›PMID 40661312›Full record

ArticleFrontiers in molecular biosciences2025

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry.

Shengsheng Li, Shenglan Qi, Rongsheng Li, Fangming Yang, Zhenyi Niu, Wei Liu, Suping Ma, Zhun Xiao

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shengsheng LiDepartment of Digestive Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Shenglan QiShanghai Key Laboratory of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Rongsheng LiShanghai Key Laboratory of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fangming YangDepartment of Digestive Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Zhenyi NiuDepartment of Pathology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Wei LiuShanghai Key Laboratory of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Suping MaDepartment of Digestive Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Zhun XiaoDepartment of Digestive Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Taohong Siwu Decoction (THSW Decoction), a classic formula for treating blood stasis, has demonstrated significant clinical efficacy in the treatment of hepatic fibrosis. However, its primary active components and mechanisms of action remain unclear. Methods: In this study, a carbon tetrachloride (CCl Results: THSW Decoction effectively reduced CCl Discussion: This study elucidates THSW Decoction's key blood components, potential targets, and mechanisms in the treatment of hepatic fibrosis, providing a foundation for further research.

Indexed as

hepatic fibrosishigh resolution mass spectrometrymicemolecular dockingnon-targeted metabolomicsTaohong Siwu decoction

Identifiers

PMID40661312
PMCPMC12256948

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.