Evidence mapPaperPMID 40661745Full record

ReviewFrontiers in endocrinology2025

The intratumor microbiota and thyroid cancer: a review.

Shan Liu, Xiaoliang Xiong, Tingting Hao, Xue Shi, Yinlong Zhao

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shan LiuDepartment of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, China.
Xiaoliang XiongDepartment of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, China.
Tingting HaoDepartment of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, China.
Xue ShiDepartment of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, China.
Yinlong ZhaoDepartment of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer is a prevalent malignancy with a rising global incidence, driven by factors such as genetic mutations, environmental influences, and gender differences. Despite advancements in diagnostic techniques and treatments, effective therapies for advanced or iodine-refractory thyroid cancer remain limited. Recent discoveries have challenged the long-held belief that tumors are sterile, revealing the presence of intratumor microbiota in various cancers. Intratumor microbiota significantly impact cancer development, immune reactions, and the effectiveness of treatments. This review examines the emerging evidence of intratumor microbiota in thyroid cancer, emphasizing their potential roles in tumor development. We also examine the origins and diversity of these microbial communities and investigate the mechanisms through which they might affect thyroid cancer progression. Understanding the complex interactions between intratumor microbiota and thyroid cancer could inform the development of novel diagnostic tools and therapeutic strategies to improve patient outcomes.

Indexed as

MicrobiotaThyroid NeoplasmsAnimalsHumansintratumor microbiotamechanismsthyroid cancertumorigenesistumor microenvironment

Identifiers

PMID40661745
PMCPMC12256260

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.