SynthesisFrontiers in human neuroscience2025
Effects of multi-site non-invasive brain stimulation on cognitive impairment after stroke: a systematic review and meta-analysis.
Synthesis in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Aberrant brain functional network in COPD patients with cognitive impairment: clinical manifestations, mechanisms and therapeutic strategies.Journal of neuroinflammation · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Post-stroke cognitive impairment (PSCI) is one of the core symptoms following a stroke, which severely affects the prognosis of patients. This systematic review and meta-analysis aim to explore the effectiveness and safety of multi-site non-invasive brain stimulation (MS-NIBS) in enhancing the cognitive function of PSCI patients. Methods: A comprehensive search was conducted in multiple databases, including MEDLINE (PubMed), Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP Database for Chinese Technical Periodicals, and Chinese Biomedical Literature Database (CBM). The search was performed up to 18 January 2025. The inclusion criteria for this meta-analysis were randomized controlled trials (RCTs) of MS-NIBS for PSCI. The primary outcome measure was the change in the global cognitive scale, while the secondary outcomes focused on improvements in attention, memory, visuospatial perception, and activities of daily living. The Cochrane Risk of Bias Tool was used to assess the quality of each eligible study. Meta-analysis and bias analysis were performed using RevMan (Version 5.3). Results: A total of 6 RCTs involving 416 samples were included in this paper. The findings from the primary outcomes revealed that the MS-NIBS group had significantly higher scores on the Montreal Cognitive Assessment (MOCA) of the cognitive composite scale (MD = 1.84, 95% CI = 1.21-2.48, Conclusion: This meta-analysis provides evidence supporting that MS-NIBS, as an emerging neuromodulatory tool, is superior to SS-NIBS in improving the overall cognitive abilities of stroke patients. However, given the limited number of included studies, it is necessary to further validate these findings through large-scale, multi-center, double-blind, and high-quality RCTs. Systematic review registration: https://www.crd.york.ac.uk/prospero/, CRD42025640015.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.