Evidence map›Paper›PMID 40662236›Full record

ArticleChemistryOpen2025

Synthesis and Anticancer Potential of New Benzimidazole Theranostic.

Sahani Sandalima Uthumange, Muhammad Azri Faiz Bin Abdul Zaki, Keng Yoon Yeong

Abstract read
In one paragraph

Article in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review of promising benzimidazole-based anticancer agents (2023-2026).Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sahani Sandalima UthumangeSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Subang Jaya, Selangor, Malaysia.ORCID 0009-0004-5324-2596
Muhammad Azri Faiz Bin Abdul ZakiSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Subang Jaya, Selangor, Malaysia.
Keng Yoon YeongSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Subang Jaya, Selangor, Malaysia.ORCID 0000-0003-0433-5070

Funding

Malaysia Ministry of Higher Education FRGS scheme FRGS/1/2020/STG04/MUSM/03/1School of Science, Monash University Malaysia
6 · The paper itself

Abstract

A series of novel benzimidazole analogs is designed, synthesized, and screened against a panel of selected cancer cell lines, including H103 (oral squamous cell carcinoma, OSCC), H314 (OSCC), and HCT116 (colorectal carcinoma). Structural characterization of the compounds is successfully confirmed using nuclear magnetic resonance spectroscopy (

Indexed as

Antineoplastic AgentsBenzimidazolesTheranostic NanomedicineCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMolecular Docking SimulationMolecular StructureSirtuin 2Structure-Activity RelationshipAntineoplastic AgentsbenzimidazoleBenzimidazolesSIRT2 protein, humanSirtuin 2anticancerbenzimidazolefluorescentselectivitysirtuin

Identifiers

PMID40662236
PMCPMC12598832

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.