Trial reportLasers in medical science2025
Treatment of neuropathic pain in leprosy patients with a physiotherapeutic protocol combined with photobiomodulation.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Photobiomodulation in chronic pain: a systematic review of randomized clinical trials.Frontiers in integrative neuroscience · 2026Pooled it
- Health-Related Quality of Life of People Living with Hansen's Disease Undergoing Multidrug Therapy.Tropical medicine and infectious disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Leprosy, when diagnosed late, often leads to persistent complications, including neuropathic pain due to Mycobacterium leprae infection. This study aimed to apply a physiotherapeutic protocol combined with photobiomodulation as a non-pharmacological resource to reduce neuropathic pain and maintain functional capacity in leprosy patients.
methodsA double-blind randomized clinical trial was conducted with 30 leprosy patients. Patients were randomly divided into two groups: physiotherapeutic protocol (PPG) and physiotherapeutic protocol combined with photobiomodulation (PPBMG). They were analyzed for simplified neurological assessment (SNA), pain scale (VAS), screening of activity limitation and safety awareness (SALSA), participation scale, and quality of life survey (SF-36).
resultsIn the SALSA, a reduction in the number of patients with severe limitation was observed in PPBMG (effect size, 0.24). In participation scale, there was an increase in the number of patients without restrictions in PPBMG. Regarding VAS, there was improvement in both groups (PPG, P = 0.0061; PPBMG, P = 0.041), with no difference between them. In relation to neurological evaluation by nerve palpation, there was improvement in the ulnar nerve condition (P = 0.0244) in PPG group, and in the fibular nerve (P = 0.0425) in PPBMG group. In the functional assessment, PPBMG patients showed statistical differences with improvement in the median (P = 0.0281) and tibial (P = 0.0267) nerves. In the SF-36, there was an increase in the domains of physical limitations (PPG, P = 0.0273; and PPBMG, P = 0.0078) and pain (PPG, P = 0.0156; and PPBMG, P = 0.0020; effect size, 0.34).
conclusionThis study provides relevant evidence for the efficacy of PPBMG in treating neuropathic pain in leprosy patients.
Indexed as
Identifiers
40663207What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.