Evidence map›Paper›PMID 40664463›Full record

ArticleFamily medicine and community health2025

Effects of age at first separation from parents on suicidal ideation, suicide planning and suicide attempts among left-behind children: the causal mediating effect of traumatic events.

Xian Wu, Xiaobing Zhai, Jiangxue Wang, Yudu Liu, Yuanyuan Wu, Yangxi Huang, Miao Zhou, Bing Xiang, Mei Yang, Xinyan Xie and 1 more

Abstract read
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Article in Family medicine and community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xian Wu *School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.ORCID 0009-0009-0677-7498
Xiaobing Zhai *Macao Polytechnic University, Macau, China.ORCID 0000-0002-4575-7360
Jiangxue WangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Yudu LiuSchool of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Yuanyuan WuHenan Provincial Orthopedic Hospital, Luoyang, Henan, China.
Yangxi HuangSchool of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, People's Republic of China.
Miao ZhouZhengzhou University, Zhengzhou, Henan, China.
Bing XiangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Mei YangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Xinyan XieSchool of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Jing Zeng *School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China zengjing@wust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the relationship of age at first separation from parents (AFSP) with suicidal ideation (SI), suicide planning (SP) and suicide attempts (SA) among left-behind children (LBC) in China and the mediating effect of traumatic events (TEs).

methodsThis cross-sectional study employed a multistage sampling method to conduct questionnaire surveys in six high-concentrated LBC provinces. Logistic regression and restricted cubic splines were performed to investigate the association of AFSP with SI, SP and SA, and meta-analysis (I

resultsA total of 12 162 (6269 LBC) participants were included in this study; the prevalence rates of SI, SP and SA among LBC were 30.7%, 18.6% and 11.9%; and LBC had a higher risk of SI (OR: 1.32), SP (OR: 1.40) and SA (OR: 1.25) than non-LBC, all p<0.001. AFSP was negatively associated with SI, SP and SA, particularly peaking before 2 years old. LBC with AFSP <2 years old had a higher risk of SI (OR 2.65; 95% CI 2.17 to 3.24; p<0.001), SP (OR 2.63; 95% CI 3.36 to 4.29; p<0.001) and SA (OR 2.04; 95% CI 2.73 to 3.63; p<0.001). TEs mediated the increased risk of SI (average causal mediation effect (ACME) 0.03-0.07; proportion (Prop) 40-54%; all p<0.001), SP (ACME 0.03-0.06; Prop 39-61%; all p<0.001) and SA (ACME 0.02-0.04; Prop 53-80%; all p<0.01).

conclusionsWe found that AFSP was associated with SI, SP and SA, mediated by TEs. Our findings supported the necessity of reducing SI, SP and SA risks among LBC and highlighted the need to consider AFSPs and TEs in intervention strategies.

Indexed as

Family SeparationSuicidal IdeationSuicide, AttemptedAdolescentAdultAge FactorsChildChinaCross-Sectional StudiesFemaleHumansMaleParentsRisk FactorsSurveys and QuestionnairesPublic HealthSuicide

Identifiers

PMID40664463
PMCPMC12265772

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.