Evidence map›Paper›PMID 40664837›Full record

ArticleScientific reports2025

Human herpes viruses are associated with steeper age-dependent increases of serum biomarkers for dementia in cognitively unimpaired women.

Lisa M James, George Stratigopoulos, Apostolos P Georgopoulos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lisa M JamesThe Healthy Brain Aging Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis HCS, One Veterans Drive, Minneapolis, MN, 55417, USA. lmjames@umn.edu.
George StratigopoulosThe Healthy Brain Aging Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis HCS, One Veterans Drive, Minneapolis, MN, 55417, USA.
Apostolos P GeorgopoulosThe Healthy Brain Aging Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis HCS, One Veterans Drive, Minneapolis, MN, 55417, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood biomarkers for dementia are being increasingly used for screening and possibly early detection of dementia in cognitively unimpaired (CU) people. Here we measured blood serum levels of 5 dementia-related biomarkers (Aβ

Indexed as

BiomarkersDementiaHerpesviridaeHerpesviridae InfectionsAdultAgedAged, 80 and overAge FactorsAmyloid beta-PeptidesCognitionFemaleHumansMiddle AgedSeroepidemiologic Studiestau ProteinsAmyloid beta-PeptidesBiomarkerstau ProteinsBlood biomarkersCognitively unimpaired agingDementiaHuman herpes viruses

Identifiers

PMID40664837
PMCPMC12263949

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.