Evidence map›Paper›PMID 40665094›Full record

ArticleScientific reports2025

Unraveling the role of shrimp hydrolysate as a food supplement in the immune function and fecal microbiota of beagle dogs.

Joana Guilherme-Fernandes, Carolina Barroso, Alexandra Correia, Tiago Aires, Timur Yergaliyev, Amélia Camarinha-Silva, Manuel Vilanova, António J M Fonseca, Sofia A C Lima, Margarida R G Maia and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Protein hydrolysates fromTranslational animal science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joana Guilherme-FernandesREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.
Carolina BarrosoREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.
Alexandra Correiai3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Tiago AiresSORGAL, Sociedade de Óleos e Rações S.A., S. João Ovar, Portugal.
Timur YergaliyevHohenheim Center for Livestock Microbiome Research, HoLMiR, University of Hohenheim, Stuttgart, Germany.
Amélia Camarinha-SilvaHohenheim Center for Livestock Microbiome Research, HoLMiR, University of Hohenheim, Stuttgart, Germany.
Manuel Vilanovai3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
António J M FonsecaREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.
Sofia A C LimaREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.
Margarida R G MaiaREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal.
Ana R J CabritaREQUIMTE, LAQV, ICBAS, School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal. arcabrita@icbas.up.pt.

Funding

Fundação para a Ciência e a Tecnologia https://doi.org/10.54499/CEECIND/01620/2017/CP1427/CT0002Fundação para a Ciência e a Tecnologia PD/BDE/150527/2019Fundação para a Ciência e a Tecnologia SFRH/BPD/70176/2010
6 · The paper itself

Abstract

The inclusion of protein hydrolysates from animal by-products in petfood may enhance the industry's sustainability, while contributing to dogs' health due to their nutritional and functional properties. However, inconsistent results of protein hydrolysates on gut microbiota, immune responses, among other health parameters, have been observed in dogs. This study aimed to evaluate the effects of diets supplemented with 5% shrimp hydrolysate, compared to non-supplemented diets, on hematological parameters, serum chemistry profile, innate and adaptive immune function, and fecal microbiota composition in adult Beagle dogs during a 12-week feeding trial. Dietary inclusion of shrimp hydrolysate decreased blood eosinophils (P = 0.017) and glucose levels (P = 0.023), while increasing levels of white blood cells (P = 0.002), platelets (P = 0.038), neutrophils (P = 0.036), and CD4

Indexed as

Dietary SupplementsFecesGastrointestinal MicrobiomePenaeidaeProtein HydrolysatesAnimal FeedAnimalsDogsFemaleMaleProtein Hydrolysates

Identifiers

PMID40665094
PMCPMC12263991

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.