Evidence map›Paper›PMID 40666145›Full record

ArticleFrontiers in public health2025

Be-SNAP: the Belgian Sepsis National Action Plan.

Annelies Mondelaers, Febe Van de Voorde, Harlinde Peperstraete, Ken Dewitte, Jan De Waele, Ilse Malfait, Patrick Van de Voorde, Erika Vlieghe

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annelies Mondelaers *Global Health Institute, University of Antwerp, Antwerp, Belgium.
Febe Van de Voorde *Department of Emergency Medicine, AZ Maria, Halle, Belgium.
Harlinde PeperstraeteDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Ken DewitteEmergency Department, AZ Voorkempen, Malle, Belgium.
Jan De WaeleDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Ilse MalfaitPatient Organisation Sepsibel vzw, Oostkamp, Belgium.
Patrick Van de VoordeDepartment of Emergency Medicine, Ghent University Hospital, Ghent, Belgium.
Erika VliegheGlobal Health Institute, University of Antwerp, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis represents a significant healthcare challenge in Belgium with an estimated 40,952 cases annually (95% CI 31,938-54,451). This life-threatening condition leads to approximately 7,675 premature deaths per year (95% CI 6,421-9,089) and a loss of 38,106 quality-adjusted life years. The economic impact is substantial with annual costs ranging from €277 million to €4.3 billion. Despite this impact, Belgium lacks a national sepsis plan until present date. Following requests from diverse professional and patient organizations yielding public and political attention, the federal minister of Health requested a scientific advice to be written (November 2023-May 2024), as a basis for a national sepsis plan. This article describes Belgium's approach to developing a National Sepsis Action Plan, highlighting evidence-based and contextualized key recommendations aimed at reducing the sepsis burden by building on existing initiatives. A multidisciplinary working group was established, including representatives of healthcare workers and professional societies representing relevant disciplines in first, second and tertiary health care settings, home care and long-term care facilities. In addition, input was sought from public health actors and experts (e.g., surveillance, vaccination programs) and patient organizations. A Haddon matrix was made and seven key topics were specified: (1) awareness, (2) prevention, (3) early warning, (4) patient management, (5) post-sepsis rehabilitation, (6) advanced care planning and (7) surveillance and research. For each item, core group members were defined. Each group conducted literature reviews and developed recommendations tailored to the Belgian healthcare system, with consensus achieved during plenary sessions. The final document was externally reviewed by national and international experts. This is the first document addressing comprehensively sepsis prevention and care in Belgium, in its diverse presentations across the community and healthcare system. The next critical steps will involve the establishment of an implementation team and design of a detailed implementation plan.

Indexed as

Health PolicySepsisBelgiumHumansadvance care planningantimicrobial stewardshipearly warninginfection prevention and controlpublic healthrapid responserehabilitationsepsis

Identifiers

PMID40666145
PMCPMC12259572

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.