ArticleNanoscale advances2025
Engineered dual-functional gold nanoparticles enhance radiosensitization in prostate cancer cells: synergistic action of curcumin and gold.
Article in Nanoscale advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Application Advances of Gold Nanoparticles in Cancer Theranostics: From Physicochemical Mechanisms to Multifunctional Nanoplatforms.International journal of molecular sciences · 2026Review
- Therapeutic Advances of Curcumin and Nanocurcumin in Glioblastoma: Molecular Targets, Bioavailability, and Drug Delivery.Nutrients · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Prostate cancer remains a leading cause of cancer-related mortality in men, with the three main treatment modalities being surgery, chemotherapy, radiotherapy, or a combination depending on the stage. However, the use of radiotherapy is often restricted by dose-limiting toxicity of the organs at risk. To address this challenge, we developed curcumin-coated gold nanoparticles (Curc-GNPs) that leverage both the photoelectric properties of gold and the radiosensitizing effects of curcumin. In this study, we explore the stability, cytotoxicity, cellular uptake, and radio-sensitizing potential of Curc-GNP in PC-3 prostate cancer cells. Curc-GNPs exhibited a biphasic dose-response curve where concentrations up to 100 μg mL
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.