ArticleBrain communications2025
MiR338-3p expression in extracellular vesicles after severe trauma with or without traumatic brain injury.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Extracellular Vesicle and Plasma miRNAs as Candidate Biomarkers of Traumatic Brain Injury in the Context of Polytrauma.International journal of molecular sciences · 2026Article
- Exosome-Based Diagnostics and Cell-Free Therapeutics for Traumatic Brain Injury: From Mechanisms to Bedside.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polytrauma and severe traumatic brain injury (TBI) are major global health burdens associated with high morbidity and mortality, requiring accurate and early diagnosis to prevent secondary complications. In polytrauma, current protein-based biomarkers for TBI lack specificity, highlighting the need for novel approaches. Circulating microRNAs, especially those encapsulated in extracellular vesicles, represent a promising alternative due to their stability and tissue-specific signatures. This study investigates compartment-specific expression of candidate microRNAs in plasma, total extracellular vesicles and neuro-derived extracellular vesicles following trauma. In this retrospective analysis, blood samples were prospectively collected from 20 trauma patients (Injury Severity Score ≥ 16;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.