Evidence map›Paper›PMID 40666752›Full record

ArticleOman journal of ophthalmology

Ocular perfusion in primary angle-closure suspect and primary angle-closure eyes without prior acute angle closure.

Reni Philip, Venkateshwaran Kannan, Lingam Vijaya, Rashima Asokan, Shantha Balekudaru, Annadurai Parivadhini, Ronnie George

Abstract read
In one paragraph

Article in Oman journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Long-term optic nerve head microvascular impairment after acute primary angle closure: an OCTA study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reni PhilipSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Venkateshwaran KannanSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Lingam VijayaSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Rashima AsokanSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Shantha BalekudaruSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Annadurai ParivadhiniSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Ronnie GeorgeSmt Jadhavbai Nathmal Singhvi Glaucoma Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute intraocular pressure (IOP) spike in acute primary angle closure (APAC) decreases ocular blood flow. It is not known if this is true in primary angle-closure (PAC) eyes without prior APAC who may have had subacute attacks. Hence, we aimed to assess the ocular perfusion using optical coherence tomography angiography (OCTA) characteristics in normal, PAC suspect (PACS), and PAC eyes without APAC. MATERIALS AND

methodsThis was a prospective cross-sectional study, which determined patients' (40-80 years) optic nerve peripapillary perfusion, flux, and macular vessel density (6 mm × 6 mm and 3 mm × 3 mm) in the superficial retinal layer on OCTA.

resultsWe included 135 eyes of 135 patients (45 per subgroup). The mean age was 59.7 ± 8.3 years. The mean peripapillary perfusion was 44.4% ±1.5% in normal, 44.2% ±1.7% in PACS, and 44.1% ±1.5% in PAC eyes. There was no significant difference between OCTA parameters among normal, PACS, and PAC eyes (

conclusionSimilar OCTA parameters were seen in normal, PACS, and PAC eyes without prior APAC, suggestive of absence of vascular factors in eyes without APAC in angle-closure disease. Functional impairment, despite similar structural and perfusion parameters in PAC eyes compared to PACS eyes, may be suggestive of ganglion cell dysfunction prior to loss.

Indexed as

Angle-closure diseaseocular perfusionprimary angle closureprimary angle-closure suspect

Identifiers

PMID40666752
PMCPMC12258828

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.