Evidence map›Paper›PMID 40666825›Full record

ReviewFood science & nutrition2025

Nutritional Influences on Brown and Beige Adipocyte: Unraveling the Molecular Mechanisms and Metabolic Implications.

Yuqun Wang, Kexin Zhang, Chengxia Kan, Wenqiang Zhang, Xiaodong Sun, Lixin Li

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuqun WangDepartment of Endocrinology and Metabolism, Shandong Provincial Key Medical and Health Discipline of Endocrinology and Laboratory of Endocrinology and Metabolic Diseases Clinical Research Center, Affiliated Hospital of Shandong Second Medical University Weifang China.
Kexin ZhangDepartment of Endocrinology and Metabolism, Shandong Provincial Key Medical and Health Discipline of Endocrinology and Laboratory of Endocrinology and Metabolic Diseases Clinical Research Center, Affiliated Hospital of Shandong Second Medical University Weifang China.
Chengxia KanDepartment of Endocrinology and Metabolism, Shandong Provincial Key Medical and Health Discipline of Endocrinology and Laboratory of Endocrinology and Metabolic Diseases Clinical Research Center, Affiliated Hospital of Shandong Second Medical University Weifang China.
Wenqiang ZhangDepartment of Endocrinology and Metabolism, Shandong Provincial Key Medical and Health Discipline of Endocrinology and Laboratory of Endocrinology and Metabolic Diseases Clinical Research Center, Affiliated Hospital of Shandong Second Medical University Weifang China.
Xiaodong SunDepartment of Endocrinology and Metabolism, Shandong Provincial Key Medical and Health Discipline of Endocrinology and Laboratory of Endocrinology and Metabolic Diseases Clinical Research Center, Affiliated Hospital of Shandong Second Medical University Weifang China.ORCID https://orcid.org/0000-0001-7775-2823
Lixin LiCollege of Health Professions, Central Michigan University Mount Pleasant Michigan USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brown adipose tissue (BAT) and beige adipose tissue (beige fat) function as thermogenic organs, significantly influencing human metabolism through various mechanisms. Recent findings suggest that dietary nutrient supplementation targeting BAT offers innovative strategies for enhancing energy homeostasis and addressing metabolic diseases. Identifying the molecular mechanisms through which nutrition regulates the function of brown and beige adipocytes is essential for translating preclinical findings into clinical applications. This review initially delineates the physiological characteristics of BAT and elucidates the regulatory mechanisms underlying its metabolic functions and associated signaling pathways. Subsequently, we examine the impact of macronutrients, micronutrients, and nutritional stimulants on BAT functionality. Finally, we explore the therapeutic potential of refined dietary strategies as future approaches for managing metabolic disorders by targeting BAT. In conclusion, nutrient-focused dietary strategies can enhance BAT function and activity, thereby contributing to the modulation of metabolic disorders and the optimization of metabolic health.

Indexed as

brown adipose tissuedietary interventionmetabolic disordersnutritionthermogenesisuncoupling protein 1

Identifiers

PMID40666825
PMCPMC12261040

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.