ArticleFrontiers in nutrition2025
The role of oxidative balance score in Cardiovascular-Kidney-Metabolic syndrome progression and mortality: insights from NHANES 1999-2020.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Interacting and joint impact of oxidative balance score and insulin resistance on cardiovascular and metabolic diseases risks: a cross-sectional, population-based study.BMC cardiovascular disorders · 2026Article
- Emerging multidimensional biomarker system for cardiovascular-kidney-metabolic syndrome: from multi-omics integration to clinical artificial intelligence.Cardiovascular diabetology · 2026Review
- A novel continuous-progression CKM model combined with multi-omics data integration identifies lipid metabolic drivers of disease progression.Frontiers in endocrinology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Cardiovascular-Kidney-Metabolic Syndrome (CKM) is a significant public health issue. This research explored the link between oxidative balance score (OBS) and the advancement of CKM, and assessed mortality risks across CKM stages in a U. S. cohort. Methods: Data from 10 NHANES cycles (1999-2020) were analyzed, including 19,433 participants for primary analysis and 16,467 for survival analysis. Multinomial regression, Cox models, survival analysis and mediation analysis were employed to evaluate the relationships. Results: The OBS was robustly associated with CKM stages, with each increment reducing the odds of CKM stages 1-4 (OR 0.93-0.90, all Conclusion: Improving oxidative balance may mitigate CKM progression and mortality risks. Additional studies are required to clarify the mechanisms and public health significance of OBS in CKM.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.