ArticleFrontiers in toxicology2025
Toxicity of glyphosate accelerates neurodegeneration in
Article in Frontiers in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Artificial Intelligence-Powered High-Content Analysis: Methodologies and Applications in Bioactive Compound Discovery from Natural Sources.Molecules (Basel, Switzerland) · 2026Review
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Authors and funding
3 authors.
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Abstract
Introduction: Pesticide-related environmental contamination poses a growing global concern, threatening human health, wildlife, and ecosystems. Glyphosate (N-phosphonomethyl-glycine, GLY), a widely used organophosphorus herbicide, has been associated with neurotoxic effects. This study investigates the potential neurodegenerative impact of glyphosate using a Caenorhabditis elegans Alzheimer's disease (AD) model. Methods: Transgenic Results: Glyphosate exposure induced a concentration-dependent decline in locomotor and feeding behaviors. Catalase activity was significantly reduced, indicating elevated oxidative stress. Additionally, a marked increase in Aβ1-42 protein expression was observed in glyphosate-treated CL4176 worms. Discussion: These findings suggest that glyphosate exacerbates Aβ toxicity and induces AD-like phenotypes in the
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Registered trials
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