SynthesisFrontiers in neurology2025
Bibliometric and visualized analysis of current advances and future directions in epilepsy: from molecular basis to therapy.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- LINAC-based stereotactic radiosurgery targeting the hippocampus in mesial temporal lobe epilepsy: a single-center case series.Chinese neurosurgical journal · 2026Article
- Nrf2 attenuates neuroinflammatory injury in intracerebral hemorrhage via an ASK1/JNK-related signaling pathway.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Through a visual analysis of the literature on epilepsy research in the Web of Science Core Collection, this study aims to explore the molecular basis, providing a reference for scholars and professionals in related fields. Methods: The search formula is generated using the Mesh keyword list in PubMed. Subsequently, English-language literature is retrieved from the Web of Science Core Collection, with the search period set from January 1, 2015, to December 31, 2024. The study calculates the annual number of publications and citations and analyzes the trends. CiteSpace 6.2. R4 software is used to perform a visual analysis of the retrieved documents. Results: The search retrieved 1,485 articles related to molecular basis of epilepsy research, with an average annual growth rate of 14.41%. Based on the publication trend line for this period, it is predicted that approximately 208 articles will be published in this field in 2025. Conclusion: This study examines the dynamic evolution of epilepsy from molecular mechanisms to clinical treatment. Ion channel abnormalities (e.g., KCNQ2 and SCN1A mutations) and neuroinflammatory pathways have become central to basic research, guiding targeted drug design. However, gaps remain between basic research and clinical application, as discoveries like circRNA regulation and glial-neuron interactions have not yet led to effective therapies, and emerging technologies such as optogenetics and nano-drug delivery systems still require clinical validation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.