ArticleFEBS letters2025
Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro-Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez-Campoy, Salvatore Adinolfi and 1 more
Abstract read
In one paragraphArticle in FEBS letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Giulia Di NapoliDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Alex FissoreDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Eleonora RaccuiaDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Simonetta Oliaro-BossoDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Alessia RuggieroInstitute of Biostructures and Bioimaging, CNR, Naples, Italy.
Milagros MedinaDepartment of Biochemistry and Molecular and Cellular Biology, School of Sciences, and Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0001-8743-0182 Adrian Velazquez-CampoyDepartment of Biochemistry and Molecular and Cellular Biology, School of Sciences, and Institute for Biocomputation and Physics of Complex Systems, University of Zaragoza, Zaragoza, Spain.
Salvatore AdinolfiDepartment of Drug Science and Technology, University of Turin, Turin, Italy.
Funding
European Commission CUP B53C20040570005European Commission CUP B53D23033100001European Union Horizon 2020 Research and Innovation Program 101004806European Union Horizon 2020 Research and Innovation Program MOSBRI-2022-134European Union Horizon 2020 Research and Innovation Program MOSBRI-23-185Government of Aragón-FEDER E35_23RThe Spanish State Research Agency and the Spanish Federation of Rare Diseases (FEDER) PID2022-136369NB-I00Università degli Studi di Torino ADIS_RILO_21_01Università degli Studi di Torino MARM_GFI_22_01_F_01Università degli Studi di Torino MARM_RILO_22_05Università degli Studi di Torino OLIS_RILO_21_02
6 · The paper itselfAbstract
Tuberculosis remains a critical global health challenge, which underscores the need for new therapeutic targets. A potential drug target is the rhodanese-like thiosulfate sulfurtransferase SseA, which plays a role in macrophage infection by Mycobacterium tuberculosis (Mtb) and its resistance to oxidative stress. In our research, we identified a protein (Rv3284), herein referred to as SufE
Indexed as
Bacterial ProteinsMycobacterium tuberculosisSulfurtransferasesThiosulfate SulfurtransferaseAmino Acid SequenceEnzyme ActivationHumansModels, MolecularProtein BindingBacterial ProteinsSulfurtransferasesThiosulfate SulfurtransferaseenzymeMycobacterium tuberculosisSseASufEMtbthiosulfate sulfurtransferase
Identifiers
PMID40667721
PMCPMC12375888
What Socratic holds
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