Evidence map›Paper›PMID 40668378›Full record

ArticlePediatric nephrology (Berlin, Germany)2026

Continuous kidney replacement therapy with CARPEDIEM

Jennifer Battista, Sergio Eleni Dit Trolli, Bruno Ranchin, Justine Bacchetta, Julien Frederic Baleine, Danièle De Luca, Stéphane Decramer, Carole Enoch, Camille Faudeux, Marc Fila and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer BattistaDepartment of Pediatric Nephrology, Unité de Néphrologie Pédiatrique, CHU de Nice, Hôpital Archet, Archet 2151 Route Saint-Antoine de Ginestière, 06200, Nice, France.
Sergio Eleni Dit TrolliDepartment of Intensive Care and Neonatal Medecine, CHU de Nice, Hôpital Archet, Nice, France.
Bruno RanchinReference Center for Rare Renal Diseases, Pediatric, Nephrology-Rheumatology-Dermatology Unit and INSERM, 1033 Unit, Hospices Civils de Lyon Femme Mere Enfant Hospital, Lyon 1 University Bron, Lyon, France.
Justine BacchettaReference Center for Rare Renal Diseases, Pediatric, Nephrology-Rheumatology-Dermatology Unit and INSERM, 1033 Unit, Hospices Civils de Lyon Femme Mere Enfant Hospital, Lyon 1 University Bron, Lyon, France.
Julien Frederic BaleineDepartment of Intensive Care and Neonatal Medecine, Montpellier, France.
Danièle De LucaDivision of Pediatrics and Neonatal Critical Care, "A. Béclère" Medical Centre, Paris Saclay University Hospitals APHP, and the Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
Stéphane DecramerPediatric Nephrology, Internal Medicine and Rheumatology, Southwest Renal Rare Diseases Centre (SORARE), University Children's Hospital, Toulouse, France.
Carole EnochPediatric Nephrology, Internal Medicine and Rheumatology, Southwest Renal Rare Diseases Centre (SORARE), University Children's Hospital, Toulouse, France.
Camille FaudeuxDepartment of Pediatric Nephrology, Unité de Néphrologie Pédiatrique, CHU de Nice, Hôpital Archet, Archet 2151 Route Saint-Antoine de Ginestière, 06200, Nice, France.
Marc FilaDepartment of Pediatric Nephrology, Hôpital Arnaud de Villeneuve, Montpellier, France.
Giulia RegiroliDivision of Pediatrics and Neonatal Critical Care, "A. Béclère" Medical Centre, Paris Saclay University Hospitals APHP, and the Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
Claus Peter SchmittFaculty of Medicine Heidelberg, Department of Pediatrics I, Pediatric Nephrology, Heidelberg University, Heidelberg, Germany.
Julie BernardorDepartment of Pediatric Nephrology, Unité de Néphrologie Pédiatrique, CHU de Nice, Hôpital Archet, Archet 2151 Route Saint-Antoine de Ginestière, 06200, Nice, France. bernardor.j@chu-nice.fr.ORCID http://orcid.org/0000-0002-1356-1507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) affects 30% of hospitalized pediatric patients, with high mortality in neonates. The Cardio-Renal Pediatric Dialysis Emergency Machine

methodsWe retrospectively evaluated the technical feasibility, efficacy regarding solute and fluid removal, tolerability and patient outcomes of CKRT with CARPEDIEM

resultsTen neonates with a median gestational age of 31 [interquartile 29-32] (range 25-38) weeks and a birth weight of 1.1 [IQ 1.0-1.7] (0.6-2.0) kilograms received continuous veno-venous hemofiltration (CVVH) during 22 sessions. CVVH was initiated at a median age of 6 [2-12] (1-72) days and a weight of 1.9 [1.5-2.4] (1.3-2.8) kg. All CVVH sessions achieved efficient blood purification. At CVVH initiation fluid overload was 29 [21-39] (11-68)% and improved until the end of treatment to 16[8-18] (0-40)% (p = 0.04). Thrombocytopenia, requiring platelet transfusion, and hypotensive episodes were the main complications observed in 14 and 13 sessions. No deaths occurred during the CARPEDIEM

conclusionCVVH using CARPEDIEM

Indexed as

Acute Kidney InjuryContinuous Renal Replacement TherapyFeasibility StudiesFemaleFranceGestational AgeHumansInfant, Low Birth WeightInfant, NewbornInfant, PrematureIntensive Care Units, PediatricMaleRegistriesRetrospective StudiesTreatment OutcomeCARPEDIEM®Continuous kidney replacement therapyLow birth weight neonate

Identifiers

PMID40668378

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.