Evidence map›Paper›PMID 40669459›Full record

ArticleCell2025

A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons.

Monika Moissidis, Leyla Abbasova, Martijn Selten, Rafael Alis, Clémence Bernard, Yaiza Domínguez-Canterla, Fazal Oozeer, Shenyue Qin, Audrey Kelly, Laura Mòdol and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  13. Review
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  15. A maturing view on interneuron development.Nature reviews. Neuroscience · 2025
    Article
  16. Heterochronous laminar maturation in the human prefrontal cortex.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Monika MoissidisCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Leyla AbbasovaCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Martijn SeltenCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Rafael AlisDevelopmental Neurobiology Unit, Instituto de Biomedicina de Valencia IBV-CSIC, Valencia 46012, Spain; Valencia Biomedical Research Foundation, Centro de Investigación Príncipe Felipe (CIPF), Associated Unit to the Instituto de Biomedicina de Valencia (IBV), Valencia 46012, Spain.
Clémence BernardCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Yaiza Domínguez-CanterlaDevelopmental Neurobiology Unit, Instituto de Biomedicina de Valencia IBV-CSIC, Valencia 46012, Spain; Valencia Biomedical Research Foundation, Centro de Investigación Príncipe Felipe (CIPF), Associated Unit to the Instituto de Biomedicina de Valencia (IBV), Valencia 46012, Spain.
Fazal OozeerCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Shenyue QinCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Audrey KellyPeter Gorer Department of Immunobiology, School of Immunology and Microbial Science, King's College London, London SE1 9RT, UK; King's Centre for Lung Health, King's College London, London SE1 9RT, UK.
Laura MòdolCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Navneet A VasisthaBiotech Research and Innovation Center (BRIC), Copenhagen Biocenter, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.
Benjamin JonesGenomics Research Platform and Single Cell Laboratory, Guy's Hospital, London SE1 9RT, UK.
Pawan DhamiGenomics Research Platform and Single Cell Laboratory, Guy's Hospital, London SE1 9RT, UK.
Konstantin KhodosevichBiotech Research and Innovation Center (BRIC), Copenhagen Biocenter, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.
Fursham HamidCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK.
Paul LavenderPeter Gorer Department of Immunobiology, School of Immunology and Microbial Science, King's College London, London SE1 9RT, UK; King's Centre for Lung Health, King's College London, London SE1 9RT, UK.
Nuria FlamesDevelopmental Neurobiology Unit, Instituto de Biomedicina de Valencia IBV-CSIC, Valencia 46012, Spain; Valencia Biomedical Research Foundation, Centro de Investigación Príncipe Felipe (CIPF), Associated Unit to the Instituto de Biomedicina de Valencia (IBV), Valencia 46012, Spain.
Oscar MarínCentre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE1 1UL, UK; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London SE1 1UL, UK. Electronic address: oscar.marin@kcl.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cortical neurons are specified during embryonic development but often acquire their mature properties at relatively late stages of postnatal development. This delay in terminal differentiation is particularly prominent for fast-spiking parvalbumin-expressing (PV

Indexed as

InterneuronsParvalbuminsAnimalsCell DifferentiationCerebral CortexGene Expression Regulation, DevelopmentalMEF2 Transcription FactorsMicePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaTranscription FactorsMef2c protein, mouseMEF2 Transcription FactorsParvalbuminsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseTranscription Factorscerebral cortexdevelopmentGABAergicgene expressioninterneuronmaturationmetabolismmitochondriaparvalbuminPGC-1α

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.