Evidence map›Paper›PMID 40670033›Full record

ReviewClinics in liver disease2025

The Liver in Hematologic Malignancies: Lymphoma, Leukemia, and Myeloma.

Natalia Zbib, Maya Gambarin-Gelwan

Abstract readReview
In one paragraph

Review in Clinics in liver disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natalia ZbibDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Gastroenterology, Hepatology and Nutrition Service, Department of Medicine, Memorial Sloan Kettering Cancer Center.
Maya Gambarin-GelwanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Gastroenterology, Hepatology and Nutrition Service, Department of Medicine, Memorial Sloan Kettering Cancer Center; Weill Cornell College of Medicine, New York, NY, USA. Electronic address: gambarim@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Liver disease significantly impacts hematologic malignancies like lymphoma, leukemia, and multiple myeloma. Chronic hepatitis B and C increase risks, complicate treatment, and may lead to reactivation during chemotherapy. Bone marrow transplantation (BMT) is associated with the risk of hepatic complications. Antiviral therapy mitigates risks, improving survival. Screening and prophylactic treatment are essential for managing liver-related complications in these patients. Cirrhosis complicates the treatment of hematologic malignancies by altering drug metabolism, increasing toxicity, and heightening risks of complications. BMT further challenges liver function, with increased risk of complications like sinusoidal obstruction syndrome, requiring specialized management.

Indexed as

Hematologic NeoplasmsLeukemiaLiver DiseasesLymphomaMultiple MyelomaBone Marrow TransplantationHepatic Veno-Occlusive DiseaseHumansLiver CirrhosisCirrhosisHepatitis BHepatitis CLympomaMetabolic dysfunction-associated steatotic liver disease (MASLD)Multiple myeloma

Identifiers

PMID40670033
PMCPMC12778112

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.