Evidence map›Paper›PMID 40670370›Full record

ArticleNPJ vaccines2025

IL-12 mRNA-LNP promotes dermal resident memory CD4

Anabel Zabala-Peñafiel, Claudia Gonzalez-Lombana, Mohamad-Gabriel Alameh, Lais A Sacramento, Zhirong Mou, Anthony T Phan, Emily A Aunins, Ying K Tam, Jude E Uzonna, Drew Weissman and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anabel Zabala-Peñafiel *Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Claudia Gonzalez-Lombana *Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Mohamad-Gabriel AlamehDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lais A SacramentoDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhirong MouDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Anthony T PhanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Emily A AuninsDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ying K TamAcuitas Therapeutics, Vancouver, BC, Canada.
Jude E UzonnaDepartment of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Drew WeissmanDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Christopher A HunterDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Phillip ScottDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. pscott@upenn.edu.

Funding

Deciphering the ontogeny of CD4+ resident memory T cells that globally seed the skin and protect against cutaneous leishmaniasisR01AI189513 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI PHILLIP SCOTT · 2025 to 2026
$1.6M
NIAID NIH HHS R01 AI189513NIH HHS RO1-AI189513
6 · The paper itself

Abstract

Dermal resident memory CD4

Identifiers

PMID40670370
PMCPMC12267433

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.