Evidence map›Paper›PMID 40670464›Full record

ArticleScientific reports2025

Association between albumin to Globulin ratio and pneumonia in patients with aneurysmal subarachnoid hemorrhage.

Yangchun Xiao, Yu Zhang, Xin Cheng, Lvlin Cheng, Yixin Tian, Jialing He, Wenqing Wang, Wenhua Tang, Chao You, Fang Fang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yangchun XiaoDepartment of Neurosurgery, Clinical Medical College and Affiliated, Hospital of Chengdu University, Chengdu, Sichuan, China.
Yu Zhang *Department of Neurosurgery, Clinical Medical College and Affiliated, Hospital of Chengdu University, Chengdu, Sichuan, China. zhangyu1057@cdu.edu.cn.
Xin ChengDepartment of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Lvlin ChengDepartment of Neurosurgery, Clinical Medical College and Affiliated, Hospital of Chengdu University, Chengdu, Sichuan, China.
Yixin TianDepartment of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Jialing HeDepartment of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Wenqing WangDepartment of Neurosurgery, Clinical Medical College and Affiliated, Hospital of Chengdu University, Chengdu, Sichuan, China.
Wenhua TangDepartment of Neurosurgery, Clinical Medical College and Affiliated, Hospital of Chengdu University, Chengdu, Sichuan, China.
Chao YouDepartment of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Fang Fang *Department of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan, China. fangfang01@scu.edu.cn.

Funding

Project Proposal for Departmental Research Projects in 2023 of Affiliated Hospital of Clinical Medicine College of Chengdu University (Y202331) Y202331
6 · The paper itself

Abstract

The albumin-to-globulin ratio (AGR) has been associated with infectious diseases; however, its association with pneumonia in patients with aneurysmal subarachnoid hemorrhage (aSAH) is unclear. This research aims to investigate the connection between AGR and hospital-acquired pneumonia (HAP). This retrospective analysis included 4,813 patients with aSAH from West China Hospital, Sichuan University. Serum samples were collected within seven days after admission. Logistic regression analysis was conducted to assess the association between AGR and HAP. Among the 4,813 patients, 1,249 (26.0%) developed HAP. The patients were classified into quartiles according to their AGR levels. Significant differences in odds ratios (ORs) were found in admission AGR: 0.76 (95% CI 0.63-0.93, p = 0.007) for Q2, 0.78 (95% CI 0.64-0.94, p = 0.016) for Q3, and 0.77 (95% CI 0.63-0.94, p = 0.012) for Q4 versus Q1. ORs of minimum AGR were: 0.67 (95% CI 0.57-0.80, p < 0.001) for Q2, 0.45(95% CI 0.37-0.54, p < 0.001) for Q3, and 0.24 (95% CI 0.20-0.30, p < 0.001) for Q4. ORs for AGR drift: 1.19 (95% CI 0.93-1.52, p = 0.18) for Q2, 1.35 (95% CI 1.06-1.73, p = 0.015) for Q3, and 2.00 (95% CI 1.57-2.55, p < 0.001) for Q4. Furthermore, admission AGR (< 1.21) and minimum AGR (< 0.99) were linked to elevated CURB-65 scores

Indexed as

GlobulinsHealthcare-Associated PneumoniaPneumoniaSerum AlbuminSerum GlobulinsSubarachnoid HemorrhageAdultAgedChinaFemaleHumansMaleMiddle AgedOdds RatioRetrospective StudiesRisk FactorsGlobulinsSerum AlbuminSerum GlobulinsAlbuminAneurysmalGlobulinPneumoniaRatioSeveritySubarachnoid hemorrhage

Identifiers

PMID40670464
PMCPMC12267572

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.