ArticleNature human behaviour2025
Speech sequencing in the human precentral gyrus.
Article in Nature human behaviour, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Simultaneous speech and gesture decoding for multimodal communication in paralysis.Nature neuroscience · 2026Article
- How speech plans become spoken sequences.Nature human behaviour · 2026Article
- Distinct neural processes link speech planning and execution.Nature human behaviour · 2026Article
- Premotor cortex uses a compositional neural geometry to plan words.bioRxiv : the preprint server for biology · 2026Article
- Decoding intended speech with an intracortical brain-computer interface in a person with long-standing anarthria and locked-in syndrome.Cell reports · 2026Article
- Neural activity flows through cortical subnetworks during speech production.Cell reports · 2026Article
- The Neural Cost of Language Processing: Broader Network Recruitment in Adults With Developmental Language Disorder.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Speech sequencing in the human precentral gyrus.Nature human behaviour · 2025Article
- Children with lower language skill engage additional brain mechanisms in both hemispheres during sentence comprehension.Research square · 2025Article
- Implications of shared motor and perceptual activations on the sensorimotor cortex for neuroprosthetic decoding.Journal of neural engineering · 2025Article
- Disrupted gray matter structural covariance networks in chronic insomnia disorder.Frontiers in psychiatry · 2025Article
- Correlation between cortical morphology and synaptic-associated proteins levels in poststroke aphasia: a pilot study.Frontiers in psychology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fluent speech production is mediated by serially ordering and preparing motor plans corresponding to target speech sounds, a process known as speech-motor sequencing. Here we used high-density direct cortical recordings while 14 participants spoke utterances with varying phonemic and syllabic sequence complexity after reading a target sequence and a delay period. Phasic activations corresponding to speech production and auditory feedback were observed, but also sustained neural activity that persisted throughout all task phases including the target presentation, the delay period and production of the sequence. Furthermore, sustained activity in a specific area, the middle precentral gyrus (mPrCG), was both modulated by sequence complexity and predicted reaction time, suggesting a role in speech-motor sequencing. Electrocortical stimulation of the mPrCG caused speech disfluencies resembling those seen in apraxia of speech. These results suggest that speech-motor sequencing is mediated by a distributed cortical network in which the mPrCG plays a central role.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.