Evidence map›Paper›PMID 40670802›Full record

ArticleEuropean biophysics journal : EBJ2026

Biological applications at the AQUA beamline of the EuPRAXIA@SPARC_LAB free electron laser.

Emiliano De Santis, Tomas André, Stefania Alleva, Richard Bean, Massimo Ferrario, Augusto Marcelli, Velia Minicozzi, Emiliano Principi, Nicuşor Tîmneanu, Carl Caleman and 1 more

Abstract read
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In one paragraph

Article in European biophysics journal : EBJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emiliano De Santis *Department of Physics, University of Rome Tor Vergata and INFN, Via della Ricerca Scientifica 1, 00133, Rome, Italy. edesantis@roma2.infn.it.ORCID http://orcid.org/0000-0001-5029-7429
Tomas André *Department of Physics and Astronomy, Uppsala University, Box 516, 75120, Uppsala, Sweden.
Stefania AllevaDepartment of Physics, University of Rome Tor Vergata and INFN, Via della Ricerca Scientifica 1, 00133, Rome, Italy.
Richard BeanEuropean XFEL GmbH, Holzkoppel 4, 22869, Schenefeld, Germany.
Massimo FerrarioINFN-LNF, Via Enrico Fermi, 00044, Frascati, Italy.
Augusto MarcelliINFN-LNF, Via Enrico Fermi, 00044, Frascati, Italy.
Velia MinicozziDepartment of Physics, University of Rome Tor Vergata and INFN, Via della Ricerca Scientifica 1, 00133, Rome, Italy.
Emiliano PrincipiElettra-Sincrotrone Trieste S.C.p.A., Strada Statale 14 - Km 163.5, Basovizza, 34149, Trieste, Italy.
Nicuşor TîmneanuDepartment of Physics and Astronomy, Uppsala University, Box 516, 75120, Uppsala, Sweden.
Carl CalemanDepartment of Physics and Astronomy, Uppsala University, Box 516, 75120, Uppsala, Sweden. carl.caleman@physics.uu.se.
Francesco StellatoDepartment of Physics, University of Rome Tor Vergata and INFN, Via della Ricerca Scientifica 1, 00133, Rome, Italy.

Funding

Horizon 2020 GA801406HORIZON EUROPE 101079773HORIZON-MSCA- 2022-DN GA101120312NAISS 2022-06725.Rö Cluster 05K22PSARö Cluster 2021-05988Swedish Research Council 2018-00740Swedish Research Council 2019-03935
6 · The paper itself

Abstract

The EuPRAXIA project is a European initiative aimed at developing groundbreaking, ultra-compact accelerator research infrastructures based on novel plasma acceleration concepts. The EuPRAXIA@SPARC_LAB facility, located in the Italian National Institute for Nuclear Physics-Frascati National Laboratory, will be the first operating Free Electron Laser facility of EuPRAXIA, based on an accelerator module driven by an electron bunch driver. The Free Electron Laser will produce ultra-short photon pulses in the soft X-ray region. The photons will be delivered to an endstation, called AQUA, to perform a wide range of experiments in atomic and molecular physics, chemistry, and life sciences for both academic and industrial users. Thanks to its wavelength, which falls within the so-called 'water window', AQUA will be particularly well-suited for coherent imaging and ion spectroscopy measurements on biological samples at room temperature in a fully hydrated environment. This unique capability opens up innovative experimental schemes for studying biological systems in states that closely resemble their physiological conditions. This paper presents numerical simulations of coherent diffraction imaging and Coulomb explosion imaging experiments, anticipating future studies at AQUA on biological samples.

Indexed as

ElectronsLasersBiosamplesCoherent diffraction imagingCoulomb explosion imagingFree electron laserWater window

Identifiers

PMID40670802
PMCPMC13109277

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.