ReviewCurrent microbiology2025
Unravelling the Gut-Microbiome-Brain Axis: Implications for Infant Neurodevelopment and Future Therapeutics.
Review in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Trial
- Cecal microbiota transportation, social stress, and injurious behaviors in chickens - A review.Poultry science · 2026Review
- Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages.Viruses · 2026Review
- Medical Gases as Emerging Regulators of Paediatric Endocrine and Neurodevelopmental Pathways: A Mini-Review.Acta paediatrica (Oslo, Norway : 1992) · 2026Review
- Vagus nerve-driven microbiota homeostasis: a promising integrative add-on therapy for neurodevelopmental disorders.Frontiers in neuroscience · 2026Article
- How gut microbiota contribute to neuropsychiatric disorders: evidence from neuroimaging studies.Frontiers in microbiology · 2026Review
- Harnessing the microbiota-gut-brain axis to prevent and treat pediatric neurodevelopmental disorders: translational insights and strategies.Journal of translational medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The microbiome-gut-brain axis signifies the intricate interplay between gut microbiome and brain, facilitated by bidirectional communication channels. The brain modulates gut function through the hypothalamic-pituitary-adrenal axis and the autonomic nervous system, while the gut influences central nervous system (CNS) function through microbial metabolites, neurotransmitters, and gut hormones. Early brain development in infants is shaped by mother to neonate microbiome transmission, mode of birth, gestational length, breastfeeding, maternal and infant antibiotic exposure, and acquired infections. Dysbiosis in the gut microbiome is associated with various neurodevelopmental disorders in children such as attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). In this review, we elucidate the pivotal role of the microbiome-gut brain axis in a child's neural development, exploring factors modulating this intricate interaction. Furthermore, we discuss the potential future therapeutic avenues that can support optimal neurodevelopment, such as probiotics, prebiotics, synbiotics, postbiotics, CRISPR/Cas9, fecal microbiota transplant, and phage therapy.
Indexed as
Identifiers
40670809What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.