ArticleDiabetology & metabolic syndrome2025
Association between morphological and mechanical properties of lower limb muscles and metabolic syndrome in type 2 diabetes.
Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Changes in Muscle Mass and Quality Mediate the Effect of High-Calorie Intake on Clinical Outcomes.Journal of cachexia, sarcopenia and muscle · 2026Article
- Fractal Analysis of Intramuscular Adipose Tissue on CT Serves as a Novel Imaging Biomarker for Metabolic Syndrome.International journal of medical sciences · 2026Article
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6 authors.
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Abstract
Metabolic syndrome (MS), a group of metabolic disorders including obesity, elevated blood pressure, abnormal blood lipid and blood glucose, is closely related to insulin resistance. Skeletal muscle is one of the important target organs of insulin, and is closely related to glucose uptake. In diabetic patients, weakened insulin signaling and elevated insulin resistance will accelerate muscle catabolism, while a high glucose state can also increase insulin resistance, thus leading to skeletal muscle atrophy and resulting in reduced skeletal muscle content or hardness. The study aims to explore the correlation between morphological and mechanical properties of lower limb muscles assessed by ultrasonic elastography and MS in populations with type 2 diabetes, and to evaluate its predictive value for MS. 516 patients with type 2 diabetes who were hospitalized in Zhongda Hospital Southeast University from December 2021 to August 2023 were included in this cross-sectional study, with a mean age of 61.87 ± 11.68 years. The median duration of diabetes in the general population was 8.0 years. Muscle thickness (MT) in MS group was significantly higher than that in non-MS group (P < 0.001), while shear wave velocity (SWV) and SWV/MT in MS group were significantly lower than those in non-MS group (P < 0.001). MT was a risk factor for MS, SWV and SWV/MT were protective factors for MS. SWV/MT in the straight position (SWV/MT
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