Evidence mapPaperPMID 40672421Full record

ReviewFrontiers in nutrition2025

Effect of dietary polyphenols along with exercise on hepatic transcriptional regulators of lipid metabolism.

YiXiao Han, ZhiHao Chen

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

YiXiao HanHenan University of Technology, Zhengzhou, China.
ZhiHao ChenCollege of Physical Education, Kunshan National University, Kunshan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing dangers of aging dyslipidemia, such as cardiovascular disease, which is one of the major causes of mortality globally, must be prevented and managed due to the detrimental consequences of age-associated dyslipidemia, particularly its dangerous effects on the cardiovascular system. Numerous studies have shown that various forms of physical activity, including strength training and moderate aerobic workouts, have a good impact on middle-aged, adult, and elderly people's lipid profiles, inflammatory responses, and cardiovascular risk. Besides exercise, natural substances found in fruits and plants, including polyphenols which have anti-inflammatory and antioxidant qualities, can also enhance health and slow down the effects of aging on changes in lipid profiles and cardiovascular irregularities. The impact of aging-related liver disease and dyslipidemia on cardiovascular abnormalities in the older population have been the subject of several research over the past 40 years. The precise mechanism of aging on the particular molecular mediators implicated in dyslipidemia in older adults has seldom been studied, despite the fact that several elements of the detrimental effects of aging on liver structure and function have been previously documented. Thus, in this study, we looked at how natural products and exercise affect hepatic transcriptional variables related to lipid metabolism.

Indexed as

curcuminhepatic transcriptional factorslipid metabolismnatural productsresveratrol

Identifiers

PMID40672421
PMCPMC12263415

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.