Evidence map›Paper›PMID 40672639›Full record

ArticleAmerican journal of translational research2025

Collateral circulation significantly improves prognosis in cerebral infarction: a meta-analysis.

Huafei Liu, Nengyun Yao, Haoyue Hu, Zhiwen Xiao, Yidi Tang, Songlin Tang

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A combined extract ofJournal of ginseng research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huafei LiuThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.
Nengyun YaoThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.
Haoyue HuThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.
Zhiwen XiaoThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.
Yidi TangThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.
Songlin TangThe No. 1 Department of Neurology, First Affiliated Hospital of Shaoyang University Shaoyang 422001, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically evaluate the association between collateral circulation and prognosis in patients with cerebral infarction through a meta-analysis.

methodsA comprehensive literature search was conducted across multiple databases to identify studies examining the relationship between collateral circulation and outcomes in cerebral infarction. Studies were screened based on predefined inclusion and exclusion criteria. Data were extracted and pooled using standard meta-analytic techniques.

resultsA total of 41 studies encompassing 10,510 patients were included. Meta-analysis revealed that good collateral circulation was significantly associated with a favorable prognosis (pooled odds ratio [OR] = 1.67, 95% confidence interval [CI]: 1.35-2.07; P < 0.001). Subgroup analyses confirmed this association across different geographic regions and sample sizes.

conclusionCollateral circulation is a critical determinant of prognosis in cerebral infarction. Enhancing collateral circulation may serve as a promising therapeutic strategy to improve clinical outcomes in affected patients.

Indexed as

cerebral infarctionCollateral circulationmeta-analysisprognosis

Identifiers

PMID40672639
PMCPMC12261181

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.