Evidence map›Paper›PMID 40675599›Full record

ArticleEndoscopy2025

Artificial intelligence for endoscopic grading of gastric intestinal metaplasia: advancing risk stratification for gastric cancer.

Eduarda Almeida, Miguel Lopes Martins, David Marques, Rose Delas, Tatiana Almeida, Jéssica Chaves, Diogo Libânio, Francesco Renna, Miguel Tavares Coimbra, Mário Dinis-Ribeiro

Abstract read
In one paragraph

Article in Endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
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  6. Review
  7. Dyspepsia followingWorld journal of gastroenterology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eduarda AlmeidaInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.ORCID 0000-0001-9273-966X
Miguel Lopes MartinsInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.
David MarquesInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.
Rose DelasInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.
Tatiana AlmeidaPrecancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI-IPOP)/CI-IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal.
Jéssica ChavesPrecancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI-IPOP)/CI-IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal.
Diogo LibânioPrecancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI-IPOP)/CI-IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal.
Francesco RennaInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.
Miguel Tavares CoimbraInstituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência - INESC TEC, Porto, Portugal.
Mário Dinis-RibeiroPrecancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI-IPOP)/CI-IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Endoscopic Grading of Gastric Intestinal Metaplasia (EGGIM) classification correlates with histological assessment of gastric intestinal metaplasia and enables stratification of gastric cancer risk. We developed and evaluated an artificial intelligence (AI) approach for EGGIM estimation. Methods: Two datasets (A and B) with 1280 narrow-band imaging images were used for per-image analysis. Still images with manually selected patches of 224 × 224 pixels, annotated by experts, were used. Dataset A was retrospectively collected from clinical routine; Dataset B (used for per-patient analysis) was prospectively collected and included 65 fully documented patients. To mimic clinical practice, a deep neural network classified image patches into three EGGIM classes (0, 1, 2) and calculated the total per-patient EGGIM score (0–10). Results: On per-image analysis, an accuracy of 87% (95%CI 71%–100%) was obtained. Per-patient EGGIM estimation had an average error of 1.15 (out of 10) and showed 88% (95%CI 80%–96%) accurate clinical decisions for surveillance (EGGIM ≥5), with 85% (95%CI 75%–94%) specificity, no false negatives, and positive and negative predictive values of 62% (95%CI 32%–92%) and 100% (95%CI 100%–100%), respectively. Conclusions: EGGIM was estimated with high accuracy using AI tools in endoscopic image analyses. Automated assessment of EGGIM may provide a greener strategy for gastric cancer risk stratification, prospective studies, and interventional trials.

Indexed as

Artificial IntelligenceGastric MucosaGastroscopyPrecancerous ConditionsStomach NeoplasmsAgedDeep LearningFemaleHumansMaleMetaplasiaMiddle AgedNarrow Band ImagingNeoplasm GradingNeural Networks, ComputerRetrospective Studies

Identifiers

PMID40675599
PMCPMC12599144

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.