Evidence map›Paper›PMID 40677097›Full record

ArticleVeterinary medicine and science2025

Application of Green Cobalt Nanoparticles in the Diet of Broiler Chickens to Improve Sustainable Production and Health.

Fayiz M Reda, Abdullah S Alawam, Hemat K Mahmoud, Mohamed T El-Saadony, Ayman S Salah, Hassan A Rudayni, Ahmed A Allam, Karima El-Naggar, Mahmoud Alagawany, Most Khairunnesa

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fayiz M RedaPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Abdullah S AlawamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Hemat K MahmoudDepartment of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Mohamed T El-SaadonyDepartment of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Ayman S SalahDepartment of Animal Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, New Valley University, El-Kharga, Egypt.
Hassan A RudayniDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Ahmed A AllamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Karima El-NaggarDepartment of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Alexandria University, Alexandria Governorate, Egypt.
Mahmoud AlagawanyPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.ORCID 0000-0002-8020-0971
Most KhairunnesaDepartment of Dairy and Poultry Science, Faculty of Veterinary Medicine and Animal Science, Gazipur Agricultural University, Gazipur, Bangladesh.ORCID 0009-0006-7214-3774

Funding

Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University IMSIU-DDRSP2501
6 · The paper itself

Abstract

backgroundNanoparticles (NPs), such as green cobalt NPs (CoNPs), are easier to pass through cell membranes in animals and interact rapidly with biological systems. Therefore, using green CoNPs is one of the recommendations for enhancing the bioavailability of cobalt, thereby improving its absorption.

objectivesThe goal of this study was to explore the influences of biological nano-cobalt (BNCo) as a feed supplement on broiler growth performance, haematology, blood chemistry, antioxidant activities, immunological status, digestive enzymes and carcass characteristics.

methodsA total of 300 Arbour Acre broiler chicks, all unsexed, were distributed into 5 treatment groups, each containing 60 chicks, at random. Five replications of each group were formed, each containing 12 chicks. The first group received a control diet free of BNCo, whereas the second, third, fourth and fifth groups were administered diets fortified with BNCo at concentrations of 100, 200, 300 and 400 ppm, respectively.

resultsThe results illustrated a significant increase in body weight (p < 0.001), body weight gain (p < 0.001) and improvement in feed conversion ratio (p < 0.01) in comparison to the control diet. BNCo supplementation significantly increased the percentage of immune organs, especially the spleen and thymus (p < 0.05, p < 0.01). Moreover, BNCo supplementation significantly increased haemoglobin (Hb) (p < 0.01), red blood cells (RBCs) (p < 0.05) and white blood cells (WBCs) (p < 0.05). In broiler chickens, BNCo supplementation increased serum levels of total protein, albumin and globulin significantly (p < 0.05) and reduced serum levels of aspartate aminotransferase (AST) activity (p < 0.001) and alanine aminotransaminase (ALT) (p < 0.01). The BNCo in feed supplementation raised blood levels of cobalt and markedly improved lipid markers, immunological and antioxidant status (p < 0.05). Furthermore, digestive enzymes were significantly boosted (p < 0.05) by BNCo treatments.

conclusionThe results indicated that BNCo supplementation at 200 ppm/kg diet produced the best overall performance, demonstrating its potential as an innovative additive for broiler diets.

Indexed as

ChickensCobaltMetal NanoparticlesNanoparticlesAnimal FeedAnimalsAntioxidantsDietDietary SupplementsMaleRandom AllocationAntioxidantsCobaltbloodbroilerdigestive enzymesgrowthnano cobalt

Identifiers

PMID40677097
PMCPMC12271835

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.