Evidence mapPaperPMID 40677207Full record

SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2025

Effects of physical exercise on metabolic syndrome in psychotic disorders: A systematic review with meta-analysis of randomized controlled trials.

Arantxa Ancín-Osés, Mikel Izquierdo, Manuel J Cuesta, Mikel L Sáez de Asteasu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arantxa Ancín-OsésNavarrabiomed, Hospital Universitario de Navarra (HUN), https://ror.org/02z0cah89Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, Spain.ORCID https://orcid.org/0009-0003-2947-6301
Mikel IzquierdoNavarrabiomed, Hospital Universitario de Navarra (HUN), https://ror.org/02z0cah89Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, Spain.ORCID https://orcid.org/0000-0002-1506-4272
Manuel J CuestaDepartment of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0003-0250-5718
Mikel L Sáez de AsteasuNavarrabiomed, Hospital Universitario de Navarra (HUN), https://ror.org/02z0cah89Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, Spain.ORCID https://orcid.org/0000-0002-4111-5045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical exercise improves mental and physical health of individuals with severe mental illness (SMI); however, its impact on metabolic syndrome remains unclear.

aimsTo evaluate the effects of exercise interventions on metabolic syndrome components in individuals with SMI and explore interactions between exercise and antipsychotic medications on metabolic outcomes.

methodsFollowing PRISMA guidelines, we systematically searched PubMed, CINAHL, Web of Science, and APA PsycINFO through October 10, 2023, for randomized controlled trials (RCTs) assessing the effects of exercise on waist circumference, blood pressure, glucose, triglycerides, and HDL cholesterol in SMI. Risk of bias was evaluated using the Cochrane RoB-2 tool. Data were pooled using random-effects models in Comprehensive Meta-Analysis and JASP.

resultsTen RCTs (

conclusionsExercise interventions did not significantly improve metabolic syndrome components in SMI. Future trials must prioritize tailored regimens, adjunctive therapies, and rigorous control of medication effects.

Indexed as

ExerciseExercise TherapyMetabolic SyndromePsychotic DisordersSchizophreniaAdultAntipsychotic AgentsHumansMiddle AgedRandomized Controlled Trials as TopicAntipsychotic Agentsmetabolic syndromephysical exercisepsychotic disorderschizophreniasevere mental disorder

Identifiers

PMID40677207
PMCPMC12344471

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.