ArticleKidney international reports2025
Effect of Exercise or Combined Exercise and Diet Intervention on Sleep and Fatigue in Kidney Transplant Recipients.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01047410 (ACtive Care After Transplantation, a Lifestyle Intervention in Renal Transplant Recipients), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ACtive Care After Transplantation, a Lifestyle Intervention in Renal Transplant Recipients
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Physical functioning and diet may be promising targets to improve sleep and reduce fatigue among kidney transplant recipients (KTRs). We investigated whether a lifestyle intervention consisting of exercise or exercise combined with diet improve self-reported sleep and fatigue among KTRs. Methods: A predefined analysis of the Dutch multicenter randomized controlled Active Care after Transplantation (ACT) study (NCT01047410) was performed. Participants were allocated to control, exercise or exercise plus diet. The exercise group received 3 months supervised exercise with 15 months lifestyle coaching. This was supplemented with 15 months dietary counseling for the exercise plus diet group. Sleep and fatigue were assessed using the Kidney Disease Quality of Life-Short Form (KDQOL-SF) and the checklist of individual strength 20 (CIS20). Results: We included 146 KTRs (36% female, mean age: 54 ± 1 yr); 44 received usual care, 57 exercise intervention, and 45 exercise plus diet intervention. Mixed model analyses showed comparable sleep and fatigue trajectories across groups. At 15 months, no effects of the exercise intervention were observed for sleep (-2.5 arbitrary units [AU], 95% confidence interval [CI]: -9.1 to 4.2) and fatigue (-1.4 AU, 95% CI: -7.0 to 4.2). Similarly, at 15 months, no effects of the exercise plus diet intervention were observed for sleep (-1.4 AU, 95% CI: -8.4 to 5.6) and fatigue (-0.2 AU, 95% CI: -6.2 to 5.8). Fatigue improved compared with baseline at all time points ( Conclusion: Although patient-reported fatigue improves in the first year posttransplantation, (severe) fatigue remains highly prevalent and persisting among KTRs. Participation in a lifestyle rehabilitation program is feasible for KTRs with severe fatigue, but it neither improves nor worsens sleep or fatigue.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.